Show simple item record

dc.contributor.authorDickinson, Alexandra J
dc.contributor.authorLehner, Kevin
dc.contributor.authorMi, Jianing
dc.contributor.authorJia, Kunpeng
dc.contributor.authorMijar, Medhavinee
dc.contributor.authorDinneny, José
dc.contributor.authorAl-Babili, Salim
dc.contributor.authorBenfey, Philip N
dc.date.accessioned2019-05-13T11:37:57Z
dc.date.available2019-05-13T11:37:57Z
dc.date.issued2019-05-08
dc.identifier.citationDickinson AJ, Lehner K, Mi J, Jia K-P, Mijar M, et al. (2019) β-Cyclocitral is a conserved root growth regulator. Proceedings of the National Academy of Sciences: 201821445. Available: http://dx.doi.org/10.1073/pnas.1821445116.
dc.identifier.issn0027-8424
dc.identifier.issn1091-6490
dc.identifier.doi10.1073/pnas.1821445116
dc.identifier.doi10.1101/337162
dc.identifier.urihttp://hdl.handle.net/10754/652858
dc.description.abstractNatural compounds capable of increasing root depth and branching are desirable tools for enhancing stress tolerance in crops. We devised a sensitized screen to identify natural metabolites capable of regulating root traits in Arabidopsis β-Cyclocitral, an endogenous root compound, was found to promote cell divisions in root meristems and stimulate lateral root branching. β-Cyclocitral rescued meristematic cell divisions in ccd1ccd4 biosynthesis mutants, and β-cyclocitral-driven root growth was found to be independent of auxin, brassinosteroid, and reactive oxygen species signaling pathways. β-Cyclocitral had a conserved effect on root growth in tomato and rice and generated significantly more compact crown root systems in rice. Moreover, β-cyclocitral treatment enhanced plant vigor in rice plants exposed to salt-contaminated soil. These results indicate that β-cyclocitral is a broadly effective root growth promoter in both monocots and eudicots and could be a valuable tool to enhance crop vigor under environmental stress.
dc.description.sponsorshipWe thank Jingyuan Zhang for technical support provided for the duration of this project; Michel Havaux, Stefano D’Alessandro, Polly Hsu, and Larry Wu for helpful discussions; Dolf Weijers, Cara Winter, Colleen Drapek, and Isaiah Taylor for critical reading; and Linxing Yao (Proteomics and Metabolomics Facility, Colorado State University) for experimental assistance. This work was supported by the Arnold and Mabel Beckman Postdoctoral Fellowship (to A.J.D.); by the Howard Hughes Medical Institute and the Gordon and Betty Moore Foundation Grant GBMF3405 (to P.N.B.); and by baseline funding and Competitive Research Grant CRG4 (to S.A.-B.) from King Abdullah University of Science and Technology.
dc.publisherProceedings of the National Academy of Sciences
dc.relation.urlhttps://www.pnas.org/content/early/2019/05/07/1821445116
dc.rightsArchived with thanks to Proceedings of the National Academy of Sciences
dc.subjectcarotenoid
dc.subjectplant hormone
dc.subjectabiotic stress
dc.subjectmeristem
dc.subjectlateral root emergence
dc.titleβ-Cyclocitral is a conserved root growth regulator
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentDesert Agriculture Initiative
dc.contributor.departmentPlant Science
dc.identifier.journalProceedings of the National Academy of Sciences
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionDepartment of Plant Biology, Carnegie Institute of Science, Stanford, CA 94305
dc.contributor.institutionHoward Hughes Medical Institute, Duke University, Durham, NC 27708
dc.contributor.institutionDepartment of Biology, Duke University, Durham, NC 27708
dc.contributor.institutionDepartment of Biology, Stanford University, Palo Alto, CA 94305
kaust.personMi, Jianing
kaust.personJia, Kunpeng
kaust.personAl-Babili, Salim
refterms.dateFOA2019-10-02T00:00:00Z
dc.date.published-online2019-05-08
dc.date.published-print2019-05-21


Files in this item

Thumbnail
Name:
1821445116.full.pdf
Size:
973.0Kb
Format:
PDF
Description:
Published version
Thumbnail
Name:
pnas.1821445116.sapp.pdf
Size:
52.75Mb
Format:
PDF
Description:
Supplemental files

This item appears in the following Collection(s)

Show simple item record