A Jasmonate Signaling Network Activates Root Stem Cells and Promotes Regeneration
Lozano-Torres, Jose L.
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Desert Agriculture Initiative
Online Publication Date2019-04-04
Print Publication Date2019-05
Permanent link to this recordhttp://hdl.handle.net/10754/631887
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AbstractPlants are sessile and have to cope with environmentally induced damage through modification of growth and defense pathways. How tissue regeneration is triggered in such responses and whether this involves stem cell activation is an open question. The stress hormone jasmonate (JA) plays well-established roles in wounding and defense responses. JA also affects growth, which is hitherto interpreted as a trade-off between growth and defense. Here, we describe a molecular network triggered by wound-induced JA that promotes stem cell activation and regeneration. JA regulates organizer cell activity in the root stem cell niche through the RBR-SCR network and stress response protein ERF115. Moreover, JA-induced ERF109 transcription stimulates CYCD6;1 expression, functions upstream of ERF115, and promotes regeneration. Soil penetration and response to nematode herbivory induce and require this JA-mediated regeneration response. Therefore, the JA tissue damage response pathway induces stem cell activation and regeneration and activates growth after environmental stress.
CitationZhou W, Lozano-Torres JL, Blilou I, Zhang X, Zhai Q, et al. (2019) A Jasmonate Signaling Network Activates Root Stem Cells and Promotes Regeneration. Cell. Available: http://dx.doi.org/10.1016/j.cell.2019.03.006.
SponsorsWe thank Lieven de Veylder, Cheng-Bin Xiang, Lin Xu, Philip Benfey, Laurent Laplaze, James A.H. Murray, Roberto Solano, and the Nottingham Arabidopsis Stock Centre for sharing research materials. We thank Casper van Schaik and Axel Kuil for experimental help. We greatly appreciated helpful discussions with Jaap Bakker, Jian Xu, Niko Geldner, and all members from the Scheres lab. This work was supported by the National Basic Research Program of China (2015CB942900 to C.L.), an EMBO long-term fellowship (ALTF 784-2014 to W.Z.), a NWO domain Applied and Engineering Sciences VENI grant (14250 to J.L.L.-T.), and the National Natural Science Foundation of China (31730010 to C.L.).