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dc.contributor.authorMarondedze, Claudius
dc.contributor.authorThomas, Ludivine
dc.contributor.authorGehring, Christoph A
dc.contributor.authorLilley, Kathryn S.
dc.date.accessioned2019-04-15T12:46:24Z
dc.date.available2019-04-15T12:46:24Z
dc.date.issued2019-04-11
dc.identifier.citationMarondedze C, Thomas L, Gehring C, Lilley KS (2019) Changes in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms. BMC Plant Biology 19. Available: http://dx.doi.org/10.1186/s12870-019-1750-x.
dc.identifier.issn1471-2229
dc.identifier.doi10.1186/s12870-019-1750-x
dc.identifier.urihttp://hdl.handle.net/10754/631883
dc.description.abstractBACKGROUND:RNA-binding proteins (RBPs) are increasingly recognized as regulatory component of post-transcriptional gene expression. RBPs interact with mRNAs via RNA-binding domains and these interactions affect RNA availability for translation, RNA stability and turn-over thus affecting both RNA and protein expression essential for developmental and stimulus specific responses. Here we investigate the effect of severe drought stress on the RNA-binding proteome to gain insights into the mechanisms that govern drought stress responses at the systems level. RESULTS:Label-free mass spectrometry enabled the identification 567 proteins of which 150 significantly responded to the drought-induced treatment. A gene ontology analysis revealed enrichment in the
dc.description.sponsorshipThe research was funded by the Office of Competitive Research Grant Program, grant number CRG3–62140383, King Abdullah University of Science and Technology (KAUST).
dc.publisherSpringer Nature
dc.relation.urlhttps://bmcplantbiol.biomedcentral.com/articles/10.1186/s12870-019-1750-x
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectArabidopsis thaliana
dc.subjectDrought stress
dc.subjectMass spectrometry
dc.subjectProteomics
dc.subjectSystems analysis
dc.subjectRNA-binding proteins
dc.subjectMrna Interactomics
dc.titleChanges in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentBioscience Core Lab
dc.contributor.departmentComputational Bioscience Research Center (CBRC)
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
dc.contributor.departmentBioscience Program
dc.identifier.journalBMC Plant Biology
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble Alpes, CEA/DRF/BIG, INRA UMR1417, CNRS UMR5168, 38054 Grenoble Cedex 9, France.
dc.contributor.institutionCambridge Centre for Proteomics, Cambridge Systems Biology Centre, and Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1GA, UK.
dc.contributor.institutionHM.Clause, rue Louis Saillant, 26802 Portes-lès-Valence, France.
dc.contributor.institutionDepartment of Chemistry, Biology and Biotechnology, University of Perugia, 74 Borgo XX Giugno, 06121 Perugia, Italy.
kaust.personMarondedze, Claudius
kaust.personThomas, Ludivine
kaust.personGehring, Christoph A.
kaust.grant.numberCRG3–62140383
dc.relation.issupplementedbyDOI:10.6084/m9.figshare.c.4468439
refterms.dateFOA2019-04-16T06:15:47Z
display.relations<b>Is Supplemented By:</b><br/> <ul><li><i>[Dataset]</i> <br/> Marondedze, C., Thomas, L., Gehring, C., &amp; Lilley, K. (2019). <i>Changes in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms</i>. Figshare. https://doi.org/10.6084/M9.FIGSHARE.C.4468439. DOI: <a href="https://doi.org/10.6084/m9.figshare.c.4468439" >10.6084/m9.figshare.c.4468439</a> Handle: <a href="http://hdl.handle.net/10754/664626" >10754/664626</a></a></li></ul>
dc.date.published-online2019-04-11
dc.date.published-print2019-12


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This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Except where otherwise noted, this item's license is described as This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.