Changes in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms
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KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionBioscience Core Lab
Computational Bioscience Research Center (CBRC)
Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
Bioscience Program
KAUST Grant Number
CRG3–62140383Date
2019-04-11Online Publication Date
2019-04-11Print Publication Date
2019-12Permanent link to this record
http://hdl.handle.net/10754/631883Metadata
Show full item recordAbstract
BACKGROUND:RNA-binding proteins (RBPs) are increasingly recognized as regulatory component of post-transcriptional gene expression. RBPs interact with mRNAs via RNA-binding domains and these interactions affect RNA availability for translation, RNA stability and turn-over thus affecting both RNA and protein expression essential for developmental and stimulus specific responses. Here we investigate the effect of severe drought stress on the RNA-binding proteome to gain insights into the mechanisms that govern drought stress responses at the systems level. RESULTS:Label-free mass spectrometry enabled the identification 567 proteins of which 150 significantly responded to the drought-induced treatment. A gene ontology analysis revealed enrichment in theCitation
Marondedze C, Thomas L, Gehring C, Lilley KS (2019) Changes in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms. BMC Plant Biology 19. Available: http://dx.doi.org/10.1186/s12870-019-1750-x.Sponsors
The research was funded by the Office of Competitive Research Grant Program, grant number CRG3–62140383, King Abdullah University of Science and Technology (KAUST).Publisher
Springer NatureJournal
BMC Plant BiologyRelations
Is Supplemented By:- [Dataset]
Marondedze, C., Thomas, L., Gehring, C., & Lilley, K. (2019). Changes in the Arabidopsis RNA-binding proteome reveal novel stress response mechanisms. Figshare. https://doi.org/10.6084/M9.FIGSHARE.C.4468439. DOI: 10.6084/m9.figshare.c.4468439 Handle: 10754/664626
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