Magnesium-Catalyzed Hydroboration of Terminal and Internal Alkynes
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2019-04-12Online Publication Date
2019-04-12Print Publication Date
2019-05-20Permanent link to this record
http://hdl.handle.net/10754/631875
Metadata
Show full item recordAbstract
A magnesium-catalyzed hydroboration of alkynes providing good yields and selectivities for a wide range of terminal and symmetrical and unsymmetrical internal alkynes has been developed. The compatibility with many functional groups makes this magnesium catalyzed procedure attractive for late stage functionalization. Experimental mechanistic investigations and DFT calculations reveal insights into the reaction mechanism of the magnesium catalyzed protocol.Citation
Magre M, Maity B, Falconnet A, Cavallo L, Rueping M (2019) Magnesium-Catalyzed Hydroboration of Terminal and Internal Alkynes. Angewandte Chemie International Edition. Available: http://dx.doi.org/10.1002/anie.201902188.Sponsors
B.M. and L.C. acknowledge King Abdullah University of Science and Technology (KAUST) for computational resources of the supercomputer Shaheen II.Publisher
WileyJournal
Angewandte ChemieAdditional Links
https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201902188ae974a485f413a2113503eed53cd6c53
10.1002/anie.201902188