Development of Low-dimensional Metal Oxide Transistors for Biochemical Sensing Applications
Name:
Wejdan Alghamdi - Thesis - Final Draft.pdf
Size:
2.304Mb
Format:
PDF
Description:
Wejdan Alghamdi - Thesis - Final Draft
Type
ThesisAuthors
Alghamdi, Wejdan S.
Advisors
Anthopoulos, Thomas D.
Committee members
McCulloch, Iain
Inal, Sahika

Program
Material Science and EngineeringKAUST Department
Physical Science and Engineering (PSE) DivisionDate
2019-03-11Embargo End Date
2020-04-11Permanent link to this record
http://hdl.handle.net/10754/631867
Metadata
Show full item recordAccess Restrictions
At the time of archiving, the student author of this thesis opted to temporarily restrict access to it. The full text of this thesis became available to the public after the expiration of the embargo on 2020-04-11.Abstract
In the last two decades, there has been considerable development for biosensor devices as the need to more efficient sensing systems is increasing for monitoring the progress of medicine and help with the early diagnosis of the pathogens and treatment of diseases that would reduce the cost of patient care. DNA sensors, in particular, have attracted attention due to their abundance of practical applications in clinical diagnoses and genetic information which increase the demand for DNA probes. On the other hand, the development of the oxide semiconductors thin film transistors (TFT) devices have been greatly increased, owing to their superior electrical properties, lower cost and large coverage areas. Building a bridge across biological elements and electronic interface using advanced (TFT) platforms are based on materials design and device architecture. Here, a solution-processed multi-layer metal oxide (TFT) is explored as a novel DNA sensor. The device engineering combines the novel hetero-structure metal oxide channel that can sustain a 2-dimensional electron gas (2DEG) which leads to a higher mobility and surface functionalization capacity to create an ultrasensitive, highly stable, and versatile DNA sensor. The prototype solid-state TFT sensor features a sub-10 nm-thick metal oxide heterojunction channel of a In2O3 and a top ZnO layer. The devices developed here rely on a pyrene-based molecule as the receptor unit that is known to intercalate into double stranded DNA with a very high-affinity constant and at very low concentration.Citation
Alghamdi, W. S. (2019). Development of Low-dimensional Metal Oxide Transistors for Biochemical Sensing Applications. KAUST Research Repository. https://doi.org/10.25781/KAUST-U9DN8ae974a485f413a2113503eed53cd6c53
10.25781/KAUST-U9DN8