Catalytic C1 Alkylation with Methanol and Isotope-Labeled Methanol
KAUST DepartmentChemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Online Publication Date2018-12-17
Print Publication Date2019-01-14
Permanent link to this recordhttp://hdl.handle.net/10754/631191
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AbstractA metal-catalyzed methylation process has been developed. By employing an air- and moisture-stable manganese catalyst together with isotopically labeled methanol, a series of D-, CD-, and C-labeled products were obtained in good yields under mild reaction conditions with water as the only byproduct.
CitationSklyaruk J, Borghs JC, El-Sepelgy O, Rueping M (2018) Catalytic C1 Alkylation with Methanol and Isotope-Labeled Methanol. Angewandte Chemie International Edition 58: 775–779. Available: http://dx.doi.org/10.1002/anie.201810885.
SponsorsJ.S. is grateful for a doctoral fellowship provided by the Fonds der Chemischen Industrie. J.C.B. acknowledges the DBU for a doctoral fellowship.