Show simple item record

dc.contributor.authorHan, Jiaojiao
dc.contributor.authorCui, Chenxi
dc.contributor.authorLi, Yanyan
dc.contributor.authorGao, Hang
dc.contributor.authorZhang, Hongyan
dc.contributor.authorZhang, Chundan
dc.contributor.authorLi, Ye
dc.contributor.authorZhou, Jun
dc.contributor.authorLu, Chenyang
dc.contributor.authorSu, Xiurong
dc.date.accessioned2018-12-31T13:54:39Z
dc.date.available2018-12-31T13:54:39Z
dc.date.issued2018-10-22
dc.identifier.citationHan J, Cui C, Li Y, Gao H, Zhang H, et al. (2018) Dietary supplement with a mixture of fish oil and krill oil has sex-dependent effects on obese mice gut microbiota. Journal of Functional Foods 51: 47–54. Available: http://dx.doi.org/10.1016/j.jff.2018.07.052.
dc.identifier.issn1756-4646
dc.identifier.doi10.1016/j.jff.2018.07.052
dc.identifier.urihttp://hdl.handle.net/10754/630618
dc.description.abstractThe intestinal microbiome is essential for human health. Significant differences in microbiota compositions have been found between individuals, but the impact that sex has on the gut microbiota alterations during obesity alleviation via fish oil and krill oil treatments is unknown. In this study, male and female high-fat-diet induced obese ICR mice received 600 μg g d fish oil, krill oil, or a mixture of both (1:1, 600 μg g d) continuously for 12 weeks. Our results indicated that the oil treatment had a greater efficacy in alleviating obesity in male mice compared with female mice, and the overall structures of the gut microbiota were notably different. Three operational taxonomic units (OTUs) were identified that were highly associated with the obesity phenotype in male mice, while 14 such OTUs were identified in female mice. These findings demonstrated that the alteration of the gut microbiota after fish and krill oil supplementation in mice is sex-associated.
dc.description.sponsorshipThis work was supported by the Natural Science Foundation of Zhejiang Province (LY18C010001), and the General Project of the Zhejiang Education Department (Y20163580), K.C. Wong Magna Fund of Ningbo University. We thank Nature Research Editing Service for English language editing.
dc.publisherElsevier BV
dc.relation.urlhttp://www.sciencedirect.com/science/article/pii/S1756464618304080
dc.subjectFish oil
dc.subjectGut microbiota
dc.subjectKrill oil
dc.subjectObesity
dc.subjectSex difference
dc.titleDietary supplement with a mixture of fish oil and krill oil has sex-dependent effects on obese mice gut microbiota
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.identifier.journalJournal of Functional Foods
dc.contributor.institutionSchool of Marine Science, Ningbo University, Ningbo, , China
dc.contributor.institutionThe First Bethune Hospital of Jilin University, Changchun, , China
kaust.personLi, Yanyan
dc.date.published-online2018-10-22
dc.date.published-print2018-12


This item appears in the following Collection(s)

Show simple item record