Genebank genomics highlights the diversity of a global barley collection
AuthorsMilner, Sara G.
Mazón, Elena Rey
Pasam, Raj K.
Krattinger, Simon G.
González, Maria Y.
Reif, Jochen C.
Permanent link to this recordhttp://hdl.handle.net/10754/629868
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AbstractGenebanks hold comprehensive collections of cultivars, landraces and crop wild relatives of all major food crops, but their detailed characterization has so far been limited to sparse core sets. The analysis of genome-wide genotyping-by-sequencing data for almost all barley accessions of the German ex situ genebank provides insights into the global population structure of domesticated barley and points out redundancies and coverage gaps in one of the world’s major genebanks. Our large sample size and dense marker data afford great power for genome-wide association scans. We detect known and novel loci underlying morphological traits differentiating barley genepools, find evidence for convergent selection for barbless awns in barley and rice and show that a major-effect resistance locus conferring resistance to bymovirus infection has been favored by traditional farmers. This study outlines future directions for genomics-assisted genebank management and the utilization of germplasm collections for linking natural variation to human selection during crop evolution.
CitationMilner SG, Jost M, Taketa S, Mazón ER, Himmelbach A, et al. (2018) Genebank genomics highlights the diversity of a global barley collection. Nature Genetics. Available: http://dx.doi.org/10.1038/s41588-018-0266-x.
SponsorsWe thank G. Matzig, J. Pohl, M. Ziems, C. Fricke, M. Kretschmann, S. König, I. Walde, G. Schütze, A. Fiebig, J. Bauernfeind, T. Münch and D. Grau for technical assistance and G. Proeseler for initiating the long-term virus testing. We are grateful to H. de Beukelaer for Corehunter support. We thank B. Schierscher-Viret from the Swiss national genebank for providing seeds and K. Lipfert for artwork. This work was supported by a grant from the Leibniz Association to N.S., U.S., H.K., A.B., A.G. and J.C.R. (Pakt für Forschung und Innovation: SAW-2015-IPK-1 ‘BRIDGE’); by the German Ministry of Education and Research (BMBF; grant 031A536 ‘de.NBI’ to U.S.); by the Young Elite Scientists Sponsorship Program (2015QNRC001) from the China Association for Science and Technology (CAST); by a grant from the China Scholarship Council to G.G.; by funding from the China Agriculture Research System (CARS-05) and the Agricultural Science and Technology Innovation Program to J.Z.; and by the Swiss Federal Office for Agriculture in the framework of the National Plan of Action for the conservation and sustainable utilization of plant genetic resources (NAP-PGREL). S.G.M. acknowledges support from the German Academic Exchange service (DAAD) through a Leibniz-DAAD fellowship. Y.J. and M.Y.G. were supported by BMBF grants 031B0184A and 031B0190A, respectively. S.F. was supported by BMBF grants to F.O. and A.Habekuß (ViReCrop, FKZ: 0315708B; COBRA, FKZ: 031A323B).