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dc.contributor.authorEl-Sepelgy, Osama
dc.contributor.authorMatador, Esteban
dc.contributor.authorBrzozowska, Aleksandra
dc.contributor.authorRueping, Magnus
dc.date.accessioned2018-09-27T07:12:29Z
dc.date.available2018-09-27T07:12:29Z
dc.date.issued2018-09-21
dc.identifier.citationEl-Sepelgy O, Matador E, Brzozowska A, Rueping M (2018) C-Alkylation of Secondary Alcohols by Primary Alcohols through Manganese-Catalyzed Double Hydrogen Autotransfer. ChemSusChem. Available: http://dx.doi.org/10.1002/cssc.201801660.
dc.identifier.issn1864-5631
dc.identifier.doi10.1002/cssc.201801660
dc.identifier.urihttp://hdl.handle.net/10754/628809
dc.description.abstractA new Mn-catalyzed alkylation of secondary alcohols with non-activated alcohols is presented. The use of a stable and well-defined manganese pincer complex, stabilized by a PNN ligand, together with a catalytic amount of base enabled the conversion of renewable alcohol feedstocks to a broad range of higher-value alcohols in good yields with water as the sole byproduct. The strategy eliminates the need for exogenous and detrimental alkyl halides as well as the use of noble metal catalysts, making the C-alkylation through double hydrogen autotransfer a highly sustainable and environmentally benign process. Mechanistic investigations support a hydrogen autotransfer mechanism in which a non-innocent ligand plays a crucial role.
dc.description.sponsorshipE.M. acknowledges Ministerio of Economía y Competitividad and Universidad de Sevilla for predoctoral fellowships.
dc.publisherWiley
dc.relation.urlhttps://onlinelibrary.wiley.com/doi/full/10.1002/cssc.201801660
dc.rightsArchived with thanks to ChemSusChem
dc.subjectalcohols
dc.subjectalkylation
dc.subjectbase metals
dc.subjecthydrogen autotransfer
dc.subjectmanganese catalysis
dc.titleC-Alkylation of Secondary Alcohols by Primary Alcohols through Manganese-Catalyzed Double Hydrogen Autotransfer
dc.typeArticle
dc.contributor.departmentKAUST Catalysis Center (KCC)
dc.identifier.journalChemSusChem
dc.eprint.versionPost-print
dc.contributor.institutionInstitute of Organic Chemistry; RWTH Aachen University; Landoltweg 1 52074 Aachen Germany
kaust.personRueping, Magnus
refterms.dateFOA2018-09-27T12:41:39Z


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