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dc.contributor.authorBrüwer, Jan David
dc.contributor.authorBuck-Wiese, Hagen
dc.date.accessioned2018-09-12T21:07:11Z
dc.date.available2018-09-12T21:07:11Z
dc.date.issued2018-08-30
dc.identifier.citationBrüwer JD, Buck-Wiese H (2018) Reading the Book of Life – Omics as a Universal Tool Across Disciplines. YOUMARES 8 – Oceans Across Boundaries: Learning from each other: 73–82. Available: http://dx.doi.org/10.1007/978-3-319-93284-2_6.
dc.identifier.doi10.1007/978-3-319-93284-2_6
dc.identifier.urihttp://hdl.handle.net/10754/628690
dc.description.abstractIn the last centuries, new high-throughput technologies, including sequencing and mass-spectrometry, have emerged and are constantly refurbished in order to decipher the molecular code of life. In this review, we summarize the physiological background from genes via transcriptome to proteins and metabolites and discuss the variety of dimensions in which a biological entity may be studied. Herein, we emphasize regulatory processes which underlie the plasticity of molecular profiles on different ome layers. We discuss the four major fields of omic research, namely genomics, transcriptomics, proteomics, and metabolomics, by providing specific examples and case studies for (i) the assessment of functionality on molecular, organism, and community level; (ii) the possibility to use omic research for categorization and systematic efforts; and (iii) the evaluation of responses to environmental cues with a special focus on anthropogenic influences. Thereby, we exemplify the knowledge gains attributable to the integration of information from different omes and the enhanced precision in predicting the phenotype. Lastly, we highlight the advantages of combining multiple omics layers in assessing the complexity of natural systems as meta-communities and -organisms.
dc.description.sponsorshipUniversität Bremen
dc.description.sponsorshipAlfred Wegener Institute Helmholtz Centre for Polar and Marine Research
dc.publisherSpringer Nature
dc.relation.urlhttps://link.springer.com/chapter/10.1007%2F978-3-319-93284-2_6
dc.rightsThis chapter is licensed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made. \n \nThe images or other third party material in this book are included in the book's Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the book's Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.
dc.subjectGenomics
dc.subjectTranscriptomics
dc.subjectProteomics
dc.subjectMetabolomics
dc.subjectMulti-meta-omics
dc.subjectPhylogeny
dc.subjectFunctionality
dc.titleReading the Book of Life – Omics as a Universal Tool Across Disciplines
dc.typeBook Chapter
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentRed Sea Research Center (RSRC)
dc.identifier.journalYOUMARES 8 – Oceans Across Boundaries: Learning from each other
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionMax Planck Institute for Marine Microbiology, Bremen, Germany
dc.contributor.institutionFaculty of Biology and Chemistry, University of Bremen, Bremen, Germany
kaust.personBrüwer, Jan David
refterms.dateFOA2018-09-13T12:41:49Z
dc.date.published-online2018-08-30
dc.date.published-print2018


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