Show simple item record

dc.contributor.authorZhang, Yi
dc.contributor.authorWustoni, Shofarul
dc.contributor.authorSavva, Achilleas
dc.contributor.authorGiovannitti, Alexander
dc.contributor.authorMcCulloch, Iain
dc.contributor.authorInal, Sahika
dc.date.accessioned2018-04-30T06:58:23Z
dc.date.available2018-04-30T06:58:23Z
dc.date.issued2018
dc.identifier.citationZhang Y, WUSTONI S, Savva A, Giovannitti A, Mcculloch I, et al. (2018) Lipid Bilayer Formation on Organic Electronic Materials. Journal of Materials Chemistry C. Available: http://dx.doi.org/10.1039/c8tc00370j.
dc.identifier.issn2050-7526
dc.identifier.issn2050-7534
dc.identifier.doi10.1039/c8tc00370j
dc.identifier.urihttp://hdl.handle.net/10754/627691
dc.description.abstractThe lipid bilayer is the elemental structure of cell membrane, forming a stable barrier between the interior and exterior of the cell while hosting membrane proteins that enable selective transport of biologically important compounds and cellular recognition. Monitoring the quality and function of lipid bilayers is thus essential and can be performed using electrically active substrates that allow for transduction of signals. Such a promising electronic transducer material is the conducting polymer poly(3,4-ethylenedioxythiophene) doped with poly(styrene sulfonate) (PEDOT:PSS) which has provided a plethora of novel bio transducing architectures. The challenge is however in assembling a bilayer on the conducting polymer surface, which is defect-free and has high mobility. Herein, we investigate the fusion of zwitterionic vesicles on a variety of PEDOT:PSS films, but also on an electron transporting, negatively charged organic semiconductor, in order to understand the surface properties that trigger vesicle fusion. The PEDOT:PSS films are prepared from dispersions containing different concentrations of ethylene glycol included as a formulation additive, which gives a handle to modulate surface physicochemical properties without a compromise on the chemical composition. The strong correlation between the polarity of the surface, the fusion of vesicles and the mobility of the resulting bilayer aides extracting design principles for the development of future conducting polymers that will enable the formation of lipid bilayers.
dc.description.sponsorshipThe authors thank Dr. Nimer Wehbe at Surface Analysis Laboratory for conducting XPS measurements.
dc.publisherRoyal Society of Chemistry (RSC)
dc.relation.urlhttp://pubs.rsc.org/en/Content/ArticleLanding/2018/TC/C8TC00370J#!divAbstract
dc.rightsArchived with thanks to Journal of Materials Chemistry C
dc.titleLipid Bilayer Formation on Organic Electronic Materials
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentBioscience Program
dc.contributor.departmentChemical Science Program
dc.contributor.departmentKAUST Solar Center (KSC)
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalJournal of Materials Chemistry C
dc.eprint.versionPost-print
dc.contributor.institutionDepartment of Chemistry and Centre for Plastic Electronics, Imperial College London, London SW7 2AZ, UK
kaust.personZhang, Yi
kaust.personWustoni, Shofarul
kaust.personSavva, Achilleas
kaust.personMcCulloch, Iain
kaust.personInal, Sahika
refterms.dateFOA2019-04-23T00:00:00Z


Files in this item

Thumbnail
Name:
c8tc00370j.pdf
Size:
1.728Mb
Format:
PDF
Description:
Accepted Manuscript
Thumbnail
Name:
c8tc00370j1.pdf
Size:
809.3Kb
Format:
PDF
Description:
Supplemental files

This item appears in the following Collection(s)

Show simple item record