KAUST DepartmentEarth Science and Engineering Program
Physical Science and Engineering (PSE) Division
Online Publication Date2017-12-01
Print Publication Date2018
Permanent link to this recordhttp://hdl.handle.net/10754/627646
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AbstractHepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.
CitationAziz AA (2018) Hepatitis C Virus. Hepatitis C in Developing Countries: 3–11. Available: http://dx.doi.org/10.1016/B978-0-12-803233-6.00001-1.