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    Hepatitis C Virus: Virology and Genotypes

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    Type
    Book Chapter
    Authors
    Abdelaziz, Ahmed
    KAUST Department
    Earth Science and Engineering Program
    Physical Science and Engineering (PSE) Division
    Date
    2017-12-01
    Online Publication Date
    2017-12-01
    Print Publication Date
    2018
    Permanent link to this record
    http://hdl.handle.net/10754/627646
    
    Metadata
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    Abstract
    Hepatitis C virus (HCV) is a major causative agent of chronic liver disease worldwide. HCV is characterized by genetic heterogeneity, with at least six genotypes identified. The geographic distribution of genotypes has shown variations in different parts of the world over the past decade because of variations in population structure, immigration, and routes of transmission. Genotype differences are of epidemiologic interest and help the study of viral transmission dynamics to trace the source of HCV infection in a given population. HCV genotypes are also of considerable clinical importance because they affect response to antiviral therapy and represent a challenging obstacle for vaccine development.
    Citation
    Aziz AA (2018) Hepatitis C Virus. Hepatitis C in Developing Countries: 3–11. Available: http://dx.doi.org/10.1016/B978-0-12-803233-6.00001-1.
    Publisher
    Elsevier BV
    Journal
    Hepatitis C in Developing Countries
    DOI
    10.1016/B978-0-12-803233-6.00001-1
    Additional Links
    http://www.sciencedirect.com/science/article/pii/3-s2.0-B9780128032336000011
    ae974a485f413a2113503eed53cd6c53
    10.1016/B978-0-12-803233-6.00001-1
    Scopus Count
    Collections
    Physical Science and Engineering (PSE) Division; Earth Science and Engineering Program; Book Chapters

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