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    CRISPR/Cas13 as a Tool for RNA Interference

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    Type
    Article
    Authors
    Ali, Zahir cc
    Mahas, Ahmed
    Mahfouz, Magdy M. cc
    KAUST Department
    Biological and Environmental Sciences and Engineering (BESE) Division
    Bioscience Program
    Desert Agriculture Initiative
    Laboratory for Genome Engineering
    Plant Science
    KAUST Grant Number
    OSR-2015-CRG4-2647
    Date
    2018-03-28
    Online Publication Date
    2018-03-28
    Print Publication Date
    2018-05
    Permanent link to this record
    http://hdl.handle.net/10754/627624
    
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    Abstract
    Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.
    Citation
    Ali Z, Mahas A, Mahfouz M (2018) CRISPR/Cas13 as a Tool for RNA Interference. Trends in Plant Science 23: 374–378. Available: http://dx.doi.org/10.1016/j.tplants.2018.03.003.
    Sponsors
    We wish to thank the Office of Sponsored Research (OSR) and King Abdullah University of Science and Technology (KAUST) for their support (award OSR-2015-CRG4-2647).
    Publisher
    Elsevier BV
    Journal
    Trends in Plant Science
    DOI
    10.1016/j.tplants.2018.03.003
    PubMed ID
    29605099
    Additional Links
    http://www.sciencedirect.com/science/article/pii/S1360138518300451
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.tplants.2018.03.003
    Scopus Count
    Collections
    Articles; Biological and Environmental Sciences and Engineering (BESE) Division; Bioscience Program; Desert Agriculture Initiative

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