• Login
    View Item 
    •   Home
    • Research
    • Articles
    • View Item
    •   Home
    • Research
    • Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Accumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    D-ll_et_al-2017-The_Plant_Journal.pdf
    Size:
    626.9Kb
    Format:
    PDF
    Description:
    Accepted Manuscript
    Download
    Type
    Article
    Authors
    Döll, Stefanie
    Kuhlmann, Markus
    Rutten, Twan
    Mette, Michael F.
    Scharfenberg, Sarah
    Petridis, Antonios
    Berreth, Dorothee-Carina
    Mock, Hans-Peter
    KAUST Department
    Biological and Environmental Sciences and Engineering (BESE) Division
    Date
    2018-01-10
    Online Publication Date
    2018-01-10
    Print Publication Date
    2018-02
    Permanent link to this record
    http://hdl.handle.net/10754/626837
    
    Metadata
    Show full item record
    Abstract
    Secondary metabolites are involved in the plant stress response. Among these are scopolin and its active form scopoletin, which are coumarin derivatives associated with reactive oxygen species scavenging and pathogen defence. Here we show that scopolin accumulation can be induced in the root by osmotic stress and in the leaf by low-temperature stress in Arabidopsis thaliana. A genetic screen for altered scopolin levels in A. thaliana revealed a mutant compromised in scopolin accumulation in response to stress; the lesion was present in a homologue of THO1 coding for a subunit of the THO/TREX complex. The THO/TREX complex contributes to RNA silencing, supposedly by trafficking precursors of small RNAs. Mutants defective in THO, AGO1, SDS3 and RDR6 were impaired with respect to scopolin accumulation in response to stress, suggesting a mechanism based on RNA silencing such as the trans-acting small interfering RNA pathway, which requires THO/TREX function.
    Citation
    Döll S, Kuhlmann M, Rutten T, Mette MF, Scharfenberg S, et al. (2018) Accumulation of the coumarin scopolin under abiotic stress conditions is mediated by the Arabidopsis thaliana THO/TREX complex. The Plant Journal. Available: http://dx.doi.org/10.1111/tpj.13797.
    Sponsors
    Funding of research by grants to H-P Mock from the EU (ATHENA; KBBE-2009-13) and the BMBF (FKZ 031A108B) are gratefully acknowledged. Antonios Petridis was supported by a post-doctoral fellowship from the Leibniz Association and the German Academic Exchange Service (DAAD). We thank the Salk Institute Genomic Analysis Laboratory for providing the sequence-indexed Arabidopsis T-DNA insertion mutants. Funding for the SIGnAL indexed insertion mutant collection was provided by the National Science Foundation. We also thank the Nottingham Arabidopsis Stock Centre, the GABI-KAT consortium and INRA Versailles for providing further seed stocks. Furthermore we are grateful for the assistance of Katja Witzel (Leibniz Institute of Vegetable and Ornamental Crops, Großbeeren, Germany) with the transcript analysis. We would also like to thank Steffen Neumann (Leibniz Institute for Plant Biochemistry, Halle, Germany) for the upload of LC-MS data into the MetaboLights database.
    Publisher
    Wiley
    Journal
    The Plant Journal
    DOI
    10.1111/tpj.13797
    Additional Links
    http://onlinelibrary.wiley.com/doi/10.1111/tpj.13797/full
    ae974a485f413a2113503eed53cd6c53
    10.1111/tpj.13797
    Scopus Count
    Collections
    Articles; Biological and Environmental Science and Engineering (BESE) Division

    entitlement

     
    DSpace software copyright © 2002-2022  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.