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    Nanoneedles for intracellular applications

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    Name:
    WO2017118921A1.pdf
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    Description:
    Published Application
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    Type
    Patent
    Patent Status
    Published Application
    Authors
    Kosel, Jürgen cc
    Kavaldzhiev, Mincho Nikolaev
    Perez, Jose Efrain
    Assignee
    King Abdullah University Of Science And Technology
    KAUST Department
    Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
    Electrical Engineering Program
    Biological and Environmental Sciences and Engineering (BESE) Division
    Bioscience Program
    Date
    2017-07-13
    Submitted Date
    2016-01-04
    Permanent link to this record
    http://hdl.handle.net/10754/626569
    
    Metadata
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    Abstract
    Nanoneedles and nanoneedle arrays and methods of making nanoneedles are provided. The methods can include multilayer fabrication methods using a negative photoresist and/or a positive photoresist. The nanoneedle arrays include one or more nanoneedles attached to a surface of a substrate. The nanoneedle can have both a proximal opening and a distal opening, and an inner passageway connecting the proximal opening and the distal opening. The nanoneedle can have a functional coating. The nanoneedle can include iron, cobalt, nickel, gold, and oxides and alloys thereof. The nanoneedle arrays can be used for the administration and/or the extraction of agents from individual cells. In one or more aspects, the nanoneedles can be magnetic nanoneedles. An oscillating magnetic field applied to a magnetic nanoneedle can induce one or both of heating and vibration of the magnetic nanoneedle. The heating and/or vibration can cause a magnetic nanoneedle to penetrate the wall of a cell.
    Application Number
    WO 2017118921 A1
    Additional Links
    http://www.google.com/patents/WO2017118921A1
    http://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2017118921A1&KC=A1&FT=D
    Collections
    Biological and Environmental Sciences and Engineering (BESE) Division; Patents; Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division

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