Manganese-Catalyzed C−H Functionalizations: Hydroarylations and Alkenylations Involving an Unexpected Heteroaryl Shift
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2017-07-17Online Publication Date
2017-07-17Print Publication Date
2017-08-07Permanent link to this record
http://hdl.handle.net/10754/625988
Metadata
Show full item recordAbstract
A manganese-catalyzed regio- and stereoselective hydroarylation of allenes is reported. The C−H functionalization method provides access to various alkenylated indoles in excellent yields. Moreover, a hydroarylation/cyclization cascade involving an unexpected C−N bond cleavage and aryl shift has been developed, which provides a new synthetic approach to substituted pyrroloindolones.Citation
Wang C, Wang A, Rueping M (2017) Manganese-Catalyzed C−H Functionalizations: Hydroarylations and Alkenylations Involving an Unexpected Heteroaryl Shift. Angewandte Chemie 129: 10067–10070. Available: http://dx.doi.org/10.1002/ange.201704682.Publisher
WileyJournal
Angewandte ChemieAdditional Links
http://onlinelibrary.wiley.com/doi/10.1002/ange.201704682/fullae974a485f413a2113503eed53cd6c53
10.1002/ange.201704682