Expedient Syntheses of Neutral and Cationic Au(I)–NHC Complexes

Type
Article

Authors
Veenboer, Richard M. P.
Gasperini, Danila
Nahra, Fady
Cordes, David B.
Slawin, Alexandra M. Z.
Cazin, Catherine S. J.
Nolan, Steven P.

Online Publication Date
2017-09-08

Print Publication Date
2017-09-25

Date
2017-09-08

Abstract
The synthesis and isolation of gold(I) precatalysts often requires the generation of several isolable intermediates as well as numerous purification steps. New protocols for the expedient synthesis of neutral [Au(OH)(NHC)] and [Au(CH2COCH3)(NHC)] species from [AuCl(NHC)] or [AuCl(DMS)] precursors bearing a variety of N-heterocyclic carbene (NHC) ligands are presented. These methods can be employed in a telescoping manner for the synthesis of catalytically relevant [Au(NTf2)(NHC)] and [Au(NHC)(NCCH3)][BF4] complexes. These attractive methods are straightforward and practical leading to various complexes in high isolated yields and purity.

Citation
Veenboer RMP, Gasperini D, Nahra F, Cordes DB, Slawin AMZ, et al. (2017) Expedient Syntheses of Neutral and Cationic Au(I)–NHC Complexes. Organometallics 36: 3645–3653. Available: http://dx.doi.org/10.1021/acs.organomet.7b00622.

Acknowledgements
The European Research Council (ERC) and the Engineering and Physical Sciences Research Council (EPSRC), UK are gratefully acknowledged for their support. Umicore AG is thanked for generous donations of auric acid. The EPSRC National Mass Spectrometry Service Centre (NMSSC) is gratefully acknowledged for HRMS analyses. S.P.N. thanks the King Abdullah University of Science and Technology (KAUST) for support. Dr Alberto Gómez Herrera is thanked for synthetic contributions.

Publisher
American Chemical Society (ACS)

Journal
Organometallics

DOI
10.1021/acs.organomet.7b00622

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