Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery

Rhamani, Saher; Chaix, Arnaud; Aggad, Dina; Hoang, Phuong; Moosa, Basem; Garcia, Marcel; Gary-Bobo, Magali; Charnay, Clarence; Almalik, Abdulaziz; Durand, Jean-Olivier; Khashab, Niveen M.

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Type

Article

Authors

Rhamani, Saher
Chaix, Arnaud
Aggad, Dina
Hoang, Phuong

Moosa, Basem

Garcia, Marcel
Gary-Bobo, Magali
Charnay, Clarence
Almalik, Abdulaziz
Durand, Jean-Olivier

Khashab, Niveen M.

KAUST Department

Advanced Membranes and Porous Materials Research Center
Chemical Engineering Program
Chemical Science Program
Physical Science and Engineering (PSE) Division
Smart Hybrid Materials (SHMs) lab

Date

2017-09-12

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http://hdl.handle.net/10754/625494

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Abstract

The synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.

Citation

Rhamani S, Chaix A, Aggad D, Hoang P, Moosa B, et al. (2017) Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery. Mol Syst Des Eng. Available: http://dx.doi.org/10.1039/c7me00058h.