Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery
Khashab, Niveen M.
KAUST DepartmentAdvanced Membranes and Porous Materials Research Center
Chemical Engineering Program
Chemical Science Program
Physical Science and Engineering (PSE) Division
Smart Hybrid Materials (SHMs) lab
Permanent link to this recordhttp://hdl.handle.net/10754/625494
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AbstractThe synthesis of gold core degradable mesoporous organosilica shell nanoparticles is described. The nanopaticles were very efficient for two-photon luminescence imaging of cancer cells and for in vitro gemcitabine monophosphate delivery, allowing promising theranostic applications in the nanomedicine field.
CitationRhamani S, Chaix A, Aggad D, Hoang P, Moosa B, et al. (2017) Gold Core Mesoporous Organosilica Shell Degradable Nanoparticles for Two-Photon Imaging and Gemcitabine Monophosphate Delivery. Mol Syst Des Eng. Available: http://dx.doi.org/10.1039/c7me00058h.
SponsorsWe thank King Abdullah University for science and Technology (KAUST) and King Abdulaziz City of Science and Technology (KACST) for the financial support. The Erasmus Mundus grant for S.R. is gratefully acknowledged. The rio imaging platform is acknowledged for technical assistance. The authors thank Dr. G. Mouchaham for Adsorption/Desorption of Nitrogen.
PublisherRoyal Society of Chemistry (RSC)
JournalMol. Syst. Des. Eng.