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dc.contributor.authorTirinato, Luca
dc.contributor.authorPagliari, Francesca
dc.contributor.authorLimongi, Tania
dc.contributor.authorMarini, Monica
dc.contributor.authorFalqui, Andrea
dc.contributor.authorSeco, J.
dc.contributor.authorCandeloro, Patrizio
dc.contributor.authorLiberale, Carlo
dc.contributor.authorDi Fabrizio, Enzo M.
dc.date.accessioned2017-08-21T06:28:04Z
dc.date.available2017-08-21T06:28:04Z
dc.date.issued2017-08-13
dc.identifier.citationTirinato L, Pagliari F, Limongi T, Marini M, Falqui A, et al. (2017) An Overview of Lipid Droplets in Cancer and Cancer Stem Cells. Stem Cells International 2017: 1–17. Available: http://dx.doi.org/10.1155/2017/1656053.
dc.identifier.issn1687-966X
dc.identifier.issn1687-9678
dc.identifier.doi10.1155/2017/1656053
dc.identifier.urihttp://hdl.handle.net/10754/625359
dc.description.abstractFor decades, lipid droplets have been considered as the main cellular organelles involved in the fat storage, because of their lipid composition. However, in recent years, some new and totally unexpected roles have been discovered for them: (i) they are active sites for synthesis and storage of inflammatory mediators, and (ii) they are key players in cancer cells and tissues, especially in cancer stem cells. In this review, we summarize the main concepts related to the lipid droplet structure and function and their involvement in inflammatory and cancer processes.
dc.description.sponsorshipThe authors acknowledge financial support from KAUST Baseline Research Funds (BAS/1-1064-01-01 and BAS/1-1066-01-01) to C. Liberale and A. Falqui, respectively, and from KAUST start-up funding (Project no. GR-2010-2320665) to E. Di Fabrizio.
dc.publisherHindawi Limited
dc.relation.urlhttps://www.hindawi.com/journals/sci/2017/1656053/
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleAn Overview of Lipid Droplets in Cancer and Cancer Stem Cells
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentBioscience Program
dc.contributor.departmentLabel-Free Optical Microscopy for Biology Lab
dc.contributor.departmentMaterial Science and Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalStem Cells International
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionGerman Cancer Research Center (DKFZ), Heidelberg, Baden-Württemberg, Germany
dc.contributor.institutionDepartment of Applied Science and Technology (DISAT), Politecnico di Torino, Torino, Italy
dc.contributor.institutionBioNEM Lab, Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy
kaust.personTirinato, Luca
kaust.personPagliari, Francesca
kaust.personLimongi, Tania
kaust.personMarini, Monica
kaust.personFalqui, Andrea
kaust.personLiberale, Carlo
kaust.personDi Fabrizio, Enzo M.
refterms.dateFOA2018-06-14T05:06:36Z
dc.date.published-online2017-08-13
dc.date.published-print2017


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This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Except where otherwise noted, this item's license is described as This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.