Di Fabrizio, Enzo M.
KAUST DepartmentPhysical Sciences and Engineering (PSE) Division
Biological and Environmental Sciences and Engineering (BESE) Division
MetadataShow full item record
AbstractFor decades, lipid droplets have been considered as the main cellular organelles involved in the fat storage, because of their lipid composition. However, in recent years, some new and totally unexpected roles have been discovered for them: (i) they are active sites for synthesis and storage of inflammatory mediators, and (ii) they are key players in cancer cells and tissues, especially in cancer stem cells. In this review, we summarize the main concepts related to the lipid droplet structure and function and their involvement in inflammatory and cancer processes.
CitationTirinato L, Pagliari F, Limongi T, Marini M, Falqui A, et al. (2017) An Overview of Lipid Droplets in Cancer and Cancer Stem Cells. Stem Cells International 2017: 1–17. Available: http://dx.doi.org/10.1155/2017/1656053.
SponsorsThe authors acknowledge financial support from KAUST Baseline Research Funds (BAS/1-1064-01-01 and BAS/1-1066-01-01) to C. Liberale and A. Falqui, respectively, and from KAUST start-up funding (Project no. GR-2010-2320665) to E. Di Fabrizio.
JournalStem Cells International
Except where otherwise noted, this item's license is described as This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.