Hall effect biosensors with ultraclean graphene film for improved sensitivity of label-free DNA detection
Type
ArticleAuthors
Loan, Phan Thi KimWu, Dongqin
Ye, Chen
Li, Xiaoqing
Tra, Vu Thanh
Wei, Qiuping
Fu, Li
Yu, Aimin
Li, Lain-Jong

Lin, Cheng-Te
KAUST Department
Material Science and Engineering ProgramPhysical Science and Engineering (PSE) Division
Date
2017-07-19Online Publication Date
2017-07-19Print Publication Date
2018-01Permanent link to this record
http://hdl.handle.net/10754/625253
Metadata
Show full item recordAbstract
The quality of graphene strongly affects the performance of graphene-based biosensors which are highly demanded for the sensitive and selective detection of biomolecules, such as DNA. This work reported a novel transfer process for preparing a residue-free graphene film using a thin gold supporting layer. A Hall effect device made of this gold-transferred graphene was demonstrated to significantly enhance the sensitivity (≈ 5 times) for hybridization detection, with a linear detection range of 1 pM – 100nM for DNA target. Our findings provide an efficient method to boost the sensitivity of graphene-based biosensors for DNA recognition.Citation
Loan PTK, Wu D, Ye C, Li X, Tra VT, et al. (2017) Hall effect biosensors with ultraclean graphene film for improved sensitivity of label-free DNA detection. Biosensors and Bioelectronics. Available: http://dx.doi.org/10.1016/j.bios.2017.07.045.Sponsors
The authors are grateful for the financial support by the National Natural Science Foundation of China (51573201, 51501209, 201675165 and 21475033), Program for International S&T Cooperation Projects of the Ministry of Science and Technology of China (2015DFA50760), Public Welfare Project of Zhejiang Province (2016C31026), Science and Technology Major Project of Ningbo (2014S10001, 2016B10038 and 2016S1002), and International S&T Cooperation Program of Ningbo (2015D10003 and 2017D10016) for financial support. We also thank the Chinese Academy of Science for Hundred Talents Program, Chinese Central Government for Thousand Young Talents Program, 3315 Program of Ningbo, The Key Technology of Nuclear Energy (CAS Interdisciplinary Innovation Team, 2014), and Vietnam National Foundation for Science and Technology Development (NAFOSTED) under grant number 103.01–2015.98.Publisher
Elsevier BVJournal
Biosensors and BioelectronicsPubMed ID
28743083Additional Links
http://www.sciencedirect.com/science/article/pii/S095656631730492Xae974a485f413a2113503eed53cd6c53
10.1016/j.bios.2017.07.045
Scopus Count
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