Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties
dc.contributor.author | Kalakonda, Parvathalu | |
dc.contributor.author | Aldhahri, Musab A. | |
dc.contributor.author | Abdel-wahab, Mohamed Shaaban | |
dc.contributor.author | Tamayol, Ali | |
dc.contributor.author | Moghaddam, K. Mollazadeh | |
dc.contributor.author | Ben Rached, Fathia | |
dc.contributor.author | Pain, Arnab | |
dc.contributor.author | Khademhosseini, Ali | |
dc.contributor.author | Memic, Adnan | |
dc.contributor.author | Chaieb, Saharoui | |
dc.date.accessioned | 2017-07-19T10:45:02Z | |
dc.date.available | 2017-07-19T10:45:02Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Kalakonda P, Aldhahri MA, Abdel-wahab MS, Tamayol A, Moghaddam KM, et al. (2017) Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties. RSC Adv 7: 34331–34338. Available: http://dx.doi.org/10.1039/c6ra25151j. | |
dc.identifier.issn | 2046-2069 | |
dc.identifier.doi | 10.1039/c6ra25151j | |
dc.identifier.uri | http://hdl.handle.net/10754/625225 | |
dc.description.abstract | Electrospun scaffolds of poly(glycerol sebacate)/poly(ε-caprolactone) (PGS/PCL) have been used for engineered tissues due to their desirable thermal and mechanical properties as well as their tunable degradability. In this paper, we fabricated micro-fibrous scaffolds from a composite of PGS/PCL using a standard electrospinning method and coated them with silver (Ag). The low temperature coating method prevented substrate melting and the Ag coating decreases the pore size and increases the diameter of fibers which resulted in enhanced thermal and mechanical properties. We further compared the mechanical properties of the composite fibrous scaffolds with different thicknesses of Ag coated scaffolds. The composite fibrous scaffold with a 275 nm Ag coating showed higher tensile modulus (E) and ultimate tensile strength (UTS) without any post-processing treatment. Lastly, potential controlled release of the Ag coating from the composite fibrous scaffolds could present interesting biomedical applications. | |
dc.description.sponsorship | This project was funded by the National Plan for Science, Technology and Innovation (MAARIFAH) – King Abdulaziz City for Science and Technology – the Kingdom of Saudi Arabia – award number (12-MED3096-3). The authors thank the Science and Technology Unit, King Abdulaziz University. PK and SC thank KAUST for its support. | |
dc.publisher | Royal Society of Chemistry (RSC) | |
dc.relation.url | http://pubs.rsc.org/en/Content/ArticleLanding/2017/RA/C6RA25151J#!divAbstract | |
dc.rights | This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence | |
dc.rights.uri | http://creativecommons.org/licenses/by-nc/3.0/ | |
dc.title | Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties | |
dc.type | Article | |
dc.contributor.department | Biological and Environmental Sciences and Engineering (BESE) Division | |
dc.contributor.department | Bioscience Program | |
dc.contributor.department | Office of the VP | |
dc.contributor.department | Pathogen Genomics Laboratory | |
dc.contributor.department | Physical Science and Engineering (PSE) Division | |
dc.identifier.journal | RSC Advances | |
dc.eprint.version | Publisher's Version/PDF | |
dc.contributor.institution | Center of Nanotechnology, King Abdulaziz University, Jeddah, Saudi Arabia | |
dc.contributor.institution | Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, USA | |
dc.contributor.institution | Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, USA | |
dc.contributor.institution | Biomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA | |
dc.contributor.institution | College of Animal Bioscience and Technology, Department of Bioindustrial Technologies, Konkuk University, Hwayang-dong, Kwangjin-gu, Seoul, Republic of Korea | |
dc.contributor.institution | Department of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia | |
dc.contributor.institution | Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 6R-2100, Berkeley, 94720 USA | |
kaust.person | Kalakonda, Parvathalu | |
kaust.person | Ben Rached, Fathia | |
kaust.person | Pain, Arnab | |
kaust.person | Chaieb, Sahraoui | |
refterms.dateFOA | 2018-06-14T02:25:45Z |
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