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dc.contributor.authorKalakonda, Parvathalu.
dc.contributor.authorAldhahri, Musab A.
dc.contributor.authorAbdel-wahab, Mohamed Shaaban
dc.contributor.authorTamayol, Ali
dc.contributor.authorMoghaddam, K. Mollazadeh
dc.contributor.authorBen Rached, Fathia
dc.contributor.authorPain, Arnab
dc.contributor.authorKhademhosseini, Ali
dc.contributor.authorMemic, Adnan
dc.contributor.authorChaieb, Saharoui
dc.date.accessioned2017-07-19T10:45:02Z
dc.date.available2017-07-19T10:45:02Z
dc.date.issued2017-07-07
dc.identifier.citationKalakonda P, Aldhahri MA, Abdel-wahab MS, Tamayol A, Moghaddam KM, et al. (2017) Microfibrous silver-coated polymeric scaffolds with tunable mechanical properties. RSC Adv 7: 34331–34338. Available: http://dx.doi.org/10.1039/c6ra25151j.
dc.identifier.issn2046-2069
dc.identifier.doi10.1039/c6ra25151j
dc.identifier.urihttp://hdl.handle.net/10754/625225
dc.description.abstractElectrospun scaffolds of poly(glycerol sebacate)/poly(ε-caprolactone) (PGS/PCL) have been used for engineered tissues due to their desirable thermal and mechanical properties as well as their tunable degradability. In this paper, we fabricated micro-fibrous scaffolds from a composite of PGS/PCL using a standard electrospinning method and coated them with silver (Ag). The low temperature coating method prevented substrate melting and the Ag coating decreases the pore size and increases the diameter of fibers which resulted in enhanced thermal and mechanical properties. We further compared the mechanical properties of the composite fibrous scaffolds with different thicknesses of Ag coated scaffolds. The composite fibrous scaffold with a 275 nm Ag coating showed higher tensile modulus (E) and ultimate tensile strength (UTS) without any post-processing treatment. Lastly, potential controlled release of the Ag coating from the composite fibrous scaffolds could present interesting biomedical applications.
dc.description.sponsorshipThis project was funded by the National Plan for Science, Technology and Innovation (MAARIFAH) – King Abdulaziz City for Science and Technology – the Kingdom of Saudi Arabia – award number (12-MED3096-3). The authors thank the Science and Technology Unit, King Abdulaziz University. PK and SC thank KAUST for its support.
dc.publisherRoyal Society of Chemistry (RSC)
dc.relation.urlhttp://pubs.rsc.org/en/Content/ArticleLanding/2017/RA/C6RA25151J#!divAbstract
dc.rightsThis Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/
dc.titleMicrofibrous silver-coated polymeric scaffolds with tunable mechanical properties
dc.typeArticle
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.identifier.journalRSC Adv.
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionCenter of Nanotechnology, King Abdulaziz University, Jeddah, Saudi Arabia
dc.contributor.institutionWyss Institute for Biologically Inspired Engineering, Harvard University, Boston, USA
dc.contributor.institutionHarvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, USA
dc.contributor.institutionBiomaterials Innovation Research Center, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA
dc.contributor.institutionCollege of Animal Bioscience and Technology, Department of Bioindustrial Technologies, Konkuk University, Hwayang-dong, Kwangjin-gu, Seoul, Republic of Korea
dc.contributor.institutionDepartment of Physics, King Abdulaziz University, Jeddah 21569, Saudi Arabia
dc.contributor.institutionLawrence Berkeley National Laboratory, 1 Cyclotron Road, Mailstop 6R-2100, Berkeley, 94720 USA
kaust.personKalakonda, Parvathalu.
kaust.personBen Rached, Fathia
kaust.personPain, Arnab
kaust.personChaieb, Saharoui
refterms.dateFOA2018-06-14T02:25:45Z


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This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence
Except where otherwise noted, this item's license is described as This Open Access Article is licensed under a Creative Commons Attribution-Non Commercial 3.0 Unported Licence