The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility
Ramirez Prado, Juan Sebastian
Mahfouz, Magdy M.
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AbstractPlant adaptive responses to changing environments involve complex molecular interplays between intrinsic and external signals. Whilst much is known on the signaling components mediating diurnal, light, and temperature controls on plant development, their influence on chromatin-based transcriptional controls remains poorly explored.In this study we show that a SWI/SNF chromatin remodeler subunit, BAF60, represses seedling growth by modulating DNA accessibility of hypocotyl cell size regulatory genes. BAF60 binds nucleosome-free regions of multiple G box-containing genes, opposing in cis the promoting effect of the photomorphogenic and thermomorphogenic regulator Phytochrome Interacting Factor 4 (PIF4) on hypocotyl elongation. Furthermore, BAF60 expression level is regulated in response to light and daily rhythms.These results unveil a short path between a chromatin remodeler and a signaling component to fine-tune plant morphogenesis in response to environmental conditions.
CitationJégu T, Veluchamy A, Ramirez-Prado JS, Rizzi-Paillet C, Perez M, et al. (2017) The Arabidopsis SWI/SNF protein BAF60 mediates seedling growth control by modulating DNA accessibility. Genome Biology 18. Available: http://dx.doi.org/10.1186/s13059-017-1246-7.
SponsorsThis work was funded by King Abdullah University of Science and Technology (KAUST) and Université Paris Sud. The IPS2 benefits from the support of the LabExSaclay Plant Sciences-SPS (ANR-10-LABX-0040-SPS).
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- Issue date: 2012 Aug
- PIF1 promotes phytochrome-regulated growth under photoperiodic conditions in Arabidopsis together with PIF3, PIF4, and PIF5.
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- Issue date: 2014 Jun
- Cryptochrome 1 interacts with PIF4 to regulate high temperature-mediated hypocotyl elongation in response to blue light.
- Authors: Ma D, Li X, Guo Y, Chu J, Fang S, Yan C, Noel JP, Liu H
- Issue date: 2016 Jan 5
- A SWI/SNF Chromatin Remodelling Protein Controls Cytokinin Production through the Regulation of Chromatin Architecture.
- Authors: Jégu T, Domenichini S, Blein T, Ariel F, Christ A, Kim SK, Crespi M, Boutet-Mercey S, Mouille G, Bourge M, Hirt H, Bergounioux C, Raynaud C, Benhamed M
- Issue date: 2015
- PIF4-mediated activation of YUCCA8 expression integrates temperature into the auxin pathway in regulating arabidopsis hypocotyl growth.
- Authors: Sun J, Qi L, Li Y, Chu J, Li C
- Issue date: 2012