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AbstractWe demonstrate the utilization of an interferometrically created nanoporous polymeric gratings as a platform for biosensing applications. Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings was fabricated by combining holographic interference patterning and APTES-functionalization of pre-polymer syrup. The successful detection of multiple biomolecules indicates that the biofunctionalized nanoporous polymeric gratings can act as biosensing platforms which are label-free, inexpensive, and applicable as high-throughput assays. Copyright © 2010 by ASME.
CitationGao T, Hsiao V, Zheng YB, Huang TJ (2010) Nanoporous Polymeric Grating-Based Biosensors. Volume 5: Energy Systems Analysis, Thermodynamics and Sustainability; NanoEngineering for Energy; Engineering to Address Climate Change, Parts A and B. Available: http://dx.doi.org/10.1115/imece2010-40928.
SponsorsThis research was supported by the Air Force Office of Scientific Research, the National Science Foundation, US Department of Agriculture (USDA/NRI), and the Penn State Center for Nanoscale Science (MRSEC). Components of this work were conducted at the Pennsylvania State University node of the NSF-funded National Nanotechnology Infrastructure Network. Y. B. Z. recognizes the support from KAUST Scholar Award and the Founder’s Prize and Grant of the American Academy of Mechanics. The authors thank Dr. Jinjie Shi, Mr. Brian Kiraly, and Dr. Xiaole Mao for helpful discussions.
JournalVolume 5: Energy Systems Analysis, Thermodynamics and Sustainability; NanoEngineering for Energy; Engineering to Address Climate Change, Parts A and B
Conference/Event nameASME 2010 International Mechanical Engineering Congress and Exposition, IMECE 2010