Ultrathin Two-Dimensional Covalent Organic Framework Nanosheets: Preparation and Application in Highly Sensitive and Selective DNA Detection
Type
ArticleAuthors
Peng, YongwuHuang, Ying
Zhu, Yihan
Chen, Bo
Wang, Liying
Lai, Zhuangchai
Zhang, Zhicheng
Zhao, Meiting
Tan, Chaoliang
Yang, Nailiang
Shao, Fangwei
Han, Yu

Zhang, Hua

KAUST Department
Advanced Membranes and Porous Materials Research CenterChemical Science Program
Nanostructured Functional Materials (NFM) laboratory
Physical Science and Engineering (PSE) Division
Date
2017-06-15Online Publication Date
2017-06-15Print Publication Date
2017-06-28Permanent link to this record
http://hdl.handle.net/10754/624891
Metadata
Show full item recordAbstract
The ability to prepare ultrathin two-dimensional (2D) covalent organic framework (COF) nanosheets (NSs) in high yield is of great importance for the further exploration of their unique properties and potential applications. Herein, by elaborately designing and choosing two flexible molecules with C3v molecular symmetry as building units, a novel imine-linked COF, namely TPA-COF, with hexagonal layered structure and sheet-like morphology, is synthesized. Since the flexible building units are integrated into the COF skeletons, the interlayer stacking becomes weak, resulting in the easy exfoliation of TPA-COF into ultrathin 2D NSs. Impressively, for the first time, the detailed structural information, i.e. the pore channels and individual building units in the NSs, is clearly visualized by using the recently developed low-dose imaging technique of transmission electron microscopy (TEM). As a proof-of-concept application, the obtained ultrathin COF NSs are used as a novel fluorescence sensing platform for the highly sensitive and selective detection of DNA.Citation
Peng Y, Huang Y, Zhu Y, Chen B, Wang L, et al. (2017) Ultrathin Two-Dimensional Covalent Organic Framework Nanosheets: Preparation and Application in Highly Sensitive and Selective DNA Detection. Journal of the American Chemical Society. Available: http://dx.doi.org/10.1021/jacs.7b04096.Sponsors
This work was supported by MOE under AcRF Tier 2 (ARC 19/15, No. MOE2014-T2-2-093; MOE2015-T2-2-057; MOE2016-T2-2-103) and AcRF Tier 1 (2016-T1-001-147; 2016-T1-002-051), NTU under Start-Up Grant (M4081296.070.500000) and iFood Research Grant (M4081458.070.500000), and Singapore Millennium Foundation in Singapore. We would like to acknowledge the Facility for Analysis, Characterization, Testing and Simulation, Nanyang Technological University, Singapore, for use of their electron microscopy facilities.Publisher
American Chemical Society (ACS)PubMed ID
28578577Additional Links
http://pubs.acs.org/doi/abs/10.1021/jacs.7b04096Relations
Is Supplemented By:- [Dataset]
. DOI: 10.5517/ccdc.csd.cc1p83tw HANDLE: 10754/663775
- [Dataset]
. DOI: 10.5517/ccdc.csd.cc1p83sv HANDLE: 10754/663777
ae974a485f413a2113503eed53cd6c53
10.1021/jacs.7b04096
Scopus Count
Related articles
- Sensitive and selective fluorometric determination of DNA by using layered hexagonal nanosheets of a covalent organic framework prepared from p-phenylenediamine and benzene-1,3,5-tricarboxaldehyde.
- Authors: Mandal TK, Parvin N, Mishra K, Mohandoss S, Lee YR
- Issue date: 2019 Nov 22
- A Scalable General Synthetic Approach toward Ultrathin Imine-Linked Two-Dimensional Covalent Organic Framework Nanosheets for Photocatalytic CO<sub>2</sub> Reduction.
- Authors: Liu W, Li X, Wang C, Pan H, Liu W, Wang K, Zeng Q, Wang R, Jiang J
- Issue date: 2019 Oct 30
- Fabricating Nanosheets and Ratiometric Detection of 5-Fluorouracil by Covalent Organic Framework Hybrid Material.
- Authors: Wang J, Qu X, Zhao L, Yan B
- Issue date: 2021 Mar 9
- Au nanoparticles deposited on ultrathin two-dimensional covalent organic framework nanosheets for in vitro and intracellular sensing.
- Authors: Tian Y, Lu Q, Guo X, Wang S, Gao Y, Wang L
- Issue date: 2020 Apr 14
- High-Yield Exfoliation of Ultrathin Two-Dimensional Ternary Chalcogenide Nanosheets for Highly Sensitive and Selective Fluorescence DNA Sensors.
- Authors: Tan C, Yu P, Hu Y, Chen J, Huang Y, Cai Y, Luo Z, Li B, Lu Q, Wang L, Liu Z, Zhang H
- Issue date: 2015 Aug 19