Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage

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Type
Article
Authors
Yue, Huifeng
Guo, Lin
Liu, Xiangqian
Rueping, Magnus cc
KAUST Department
Physical Sciences and Engineering (PSE) Division
Chemical Science Program
KAUST Catalysis Center (KCC)
Date
2017-03-13

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Abstract
A nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.
Citation
Yue H, Guo L, Liu X, Rueping M (2017) Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage. Organic Letters 19: 1788–1791. Available: http://dx.doi.org/10.1021/acs.orglett.7b00556.
Sponsors
H.Y., L.G., and X.L. were supported by the China Scholarship Council. Financial support by KAUST is gratefully acknowledged.
Publisher
American Chemical Society (ACS)
Journal
Organic Letters
ISSN
1523-7060
1523-7052
DOI
10.1021/acs.orglett.7b00556
Handle URI
http://hdl.handle.net/10754/623870
Additional Links
http://pubs.acs.org/doi/full/10.1021/acs.orglett.7b00556
Collections
Articles; Physical Sciences and Engineering (PSE) Division; Chemical Science Program; KAUST Catalysis Center (KCC)