Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage
KAUST DepartmentChemical Science Program
KAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Online Publication Date2017-03-13
Print Publication Date2017-04-07
Permanent link to this recordhttp://hdl.handle.net/10754/623870
MetadataShow full item record
AbstractA nickel-catalyzed protocol for the conversion of aryl and heteroaryl alcohol derivatives to primary and secondary aromatic amines via C(sp2)-O bond cleavage is described. The new amination protocol can be applied to a range of substrates bearing diverse functional groups and uses readily available benzophenone imines as an effective nitrogen source.
CitationYue H, Guo L, Liu X, Rueping M (2017) Nickel-Catalyzed Synthesis of Primary Aryl and Heteroaryl Amines via C–O Bond Cleavage. Organic Letters 19: 1788–1791. Available: http://dx.doi.org/10.1021/acs.orglett.7b00556.
SponsorsH.Y., L.G., and X.L. were supported by the China Scholarship Council. Financial support by KAUST is gratefully acknowledged.
PublisherAmerican Chemical Society (ACS)