Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums

Abstract
An example for the catalytic synthesis of densely functionalized 1,2,3-triazoles through a LUMO activation mode has been developed. The protocol is enabled by intermolecular cross coupling reactions of azides with in situ-generated alpha,beta-unsaturated acyl azoliums. High yields and broad scope as well as the investigation of reaction mechanism are reported.

Citation
Li W, Ajitha MJ, Lang M, Huang K-W, Wang J (2017) Catalytic Intermolecular Cross-Couplings of Azides and LUMO-Activated Unsaturated Acyl Azoliums. ACS Catalysis 7: 2139–2144. Available: http://dx.doi.org/10.1021/acscatal.6b03674.

Acknowledgements
Generous financial supports are provided by the National Natural Science Foundation of China (21672121, 21502043), the

Publisher
American Chemical Society (ACS)

Journal
ACS Catalysis

DOI
10.1021/acscatal.6b03674

Additional Links
http://pubs.acs.org/doi/abs/10.1021/acscatal.6b03674

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