Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2017-03-15Online Publication Date
2017-03-15Print Publication Date
2017-04-03Permanent link to this record
http://hdl.handle.net/10754/623218
Metadata
Show full item recordAbstract
An efficient nickel-catalyzed decarbonylative amination reaction of aryl and heteroaryl esters has been achieved for the first time. The new amination protocol allows the direct interconversion of esters and amides into the corresponding amines and represents a good alternative to classical rearrangements as well as cross coupling reactions.Citation
Yue H, Guo L, Liao H-H, Cai Y, Zhu C, et al. (2017) Catalytic Ester and Amide to Amine Interconversion: Nickel-Catalyzed Decarbonylative Amination of Esters and Amides by C−O and C−C Bond Activation. Angewandte Chemie International Edition 56: 4282–4285. Available: http://dx.doi.org/10.1002/anie.201611819.Sponsors
H.Y. and L.G. acknowledge the China Scholarship Council. H.-H.L. acknowledges the DAAD for a doctoral fellowship, Y.C. acknowledges the Alexander von Humboldt-Foundation for a fellowship. Support by King Abdullah University of Science and Technology (KAUST) is gratefully acknowledged.Publisher
WileyJournal
Angewandte ChemieAdditional Links
http://onlinelibrary.wiley.com/doi/10.1002/anie.201611819/fullae974a485f413a2113503eed53cd6c53
10.1002/anie.201611819