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Nanoplasmonic and Microfluidic Devices for Biological Sensing

dc.contributor.authorPerozziello, G.
dc.contributor.authorGiugni, Andrea
dc.contributor.authorAllione, Marco
dc.contributor.authorTorre, Bruno
dc.contributor.authorDas, Gobind
dc.contributor.authorColuccio, M. L.
dc.contributor.authorMarini, Monica
dc.contributor.authorTirinato, Luca
dc.contributor.authorMoretti, Manola
dc.contributor.authorLimongi, Tania
dc.contributor.authorCandeloro, P.
dc.contributor.authorDi Fabrizio, Enzo M.
dc.date.accessioned2017-04-13T11:51:00Z
dc.date.available2017-04-13T11:51:00Z
dc.date.issued2017-02-17
dc.identifier.citationPerozziello G, Giugni A, Allione M, Torre B, Das G, et al. (2017) Nanoplasmonic and Microfluidic Devices for Biological Sensing. Nano-Optics: Principles Enabling Basic Research and Applications: 247–274. Available: http://dx.doi.org/10.1007/978-94-024-0850-8_12.
dc.identifier.issn1874-6500
dc.identifier.issn1874-6535
dc.identifier.doi10.1007/978-94-024-0850-8_12
dc.identifier.urihttp://hdl.handle.net/10754/623189
dc.description.abstractIn this chapter we report about recent advances on the development and application of 2D and 3D plasmonic nanostructures used for sensing of biological samples by Raman spectroscopy at unprecedented resolution of analysis. Besides, we explain how the integration of these nanodevices in a microfluidic apparatus can simplify the analysis of biological samples. In the first part we introduce and motivate the convenience of using nanoplasmonic enhancers and Raman spectroscopy for biological sensing, describing the phenomena and the current approaches to fabricate nanoplasmonic structures. In the second part, we explain how specific multi-element devices produce the optimal enhancement of the Raman scattering. We report cases where biological sensing of DNA was performed at few molecules level with nanometer spatial resolutions. Finally, we show an example of microfluidic device integrating plasmonic nanodevices to sort and drive biological samples, like living cells, towards the optical probe in order to obtain optimal conditions of analysis.
dc.description.sponsorshipWe acknowledge all contributors that contributed in this work from other institution, in particular the researchers from the previous Nanostructure Division at IIT (Italian Institute of Technology) in Genoa. We thank for the financial support the King Abdullah University of Science and Technology start-up fund and the Italian Minister of Health (projects nos. GR-2010-2320665 and GR-2010-2311677)
dc.publisherSpringer Nature
dc.relation.urlhttp://link.springer.com/chapter/10.1007/978-94-024-0850-8_12
dc.rightsThe final publication is available at Springer via http://dx.doi.org/10.1007/978-94-024-0850-8_12
dc.titleNanoplasmonic and Microfluidic Devices for Biological Sensing
dc.typeBook Chapter
dc.contributor.departmentBiological and Environmental Sciences and Engineering (BESE) Division
dc.contributor.departmentMaterial Science and Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalNATO Science for Peace and Security Series B: Physics and Biophysics
dc.eprint.versionPost-print
dc.contributor.institutionBionem Lab, Departement of Experimental Clinics, Campus “Salvatore Venuta”, University Magna Graecia, 88100 Germaneto-Catanzaro, Italy
kaust.personGiugni, Andrea
kaust.personAllione, Marco
kaust.personTorre, Bruno
kaust.personDas, Gobind
kaust.personMarini, Monica
kaust.personTirinato, Luca
kaust.personMoretti, Manola
kaust.personLimongi, Tania
kaust.personDi Fabrizio, Enzo M.
refterms.dateFOA2018-02-17T00:00:00Z
dc.date.published-online2017-02-17
dc.date.published-print2017


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