Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: From Nanospheres to Nanowires
Type
ArticleKAUST Department
Advanced Membranes and Porous Materials Research CenterBioscience Program
Chemical Science Program
Investment Fund
Physical Science and Engineering (PSE) Division
Smart Hybrid Materials (SHMs) lab
Date
2017-01-31Online Publication Date
2017-01-31Print Publication Date
2017-04Permanent link to this record
http://hdl.handle.net/10754/623170
Metadata
Show full item recordAbstract
This work describes the sol-gel syntheses of para-substituted phenylene-bridged periodic mesoporous organosilica (PMO) nanoparticles (NPs) with tunable morphologies ranging from nanowires to nanospheres. The findings show the key role of the addition of organic co-solvents in the aqueous templates on the final morphologies of PMO NPs. Other factors such as the temperature, the stirring speed, and the amount of organic solvents also influence the shape of PMO NPs. The tuning of the shape of the PMO nanomaterials made it possible to study the influence of the particle morphology on the cellular internalization and biocompatibility.Citation
Fatieiev Y, Croissant JG, Alamoudi K, Khashab NM (2017) Cellular Internalization and Biocompatibility of Periodic Mesoporous Organosilica Nanoparticles with Tunable Morphologies: From Nanospheres to Nanowires. ChemPlusChem. Available: http://dx.doi.org/10.1002/cplu.201600560.Sponsors
We gratefully acknowledge support from King Abdullah University of Science and Technology (KAUST), and NSF Grant DBI-1266377. We thank Haneen Omar for her support in the XRD measurements.Publisher
WileyJournal
ChemPlusChemAdditional Links
http://onlinelibrary.wiley.com/doi/10.1002/cplu.201600560/fullae974a485f413a2113503eed53cd6c53
10.1002/cplu.201600560