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dc.contributor.authorChatupheeraphat, Adisak
dc.contributor.authorLiao, Hsuan-Hung
dc.contributor.authorMader, Steffen
dc.contributor.authorSako, Makoto
dc.contributor.authorSasai, Hiroaki
dc.contributor.authorAtodiresei, Iuliana
dc.contributor.authorRueping, Magnus
dc.date.accessioned2017-04-13T11:50:57Z
dc.date.available2017-04-13T11:50:57Z
dc.date.issued2016-03-08
dc.identifier.citationChatupheeraphat A, Liao H-H, Mader S, Sako M, Sasai H, et al. (2016) Asymmetric Brønsted Acid Catalyzed Substitution of Diaryl Methanols with Thiols and Alcohols for the Synthesis of Chiral Thioethers and Ethers. Angewandte Chemie International Edition 55: 4803–4807. Available: http://dx.doi.org/10.1002/anie.201511179.
dc.identifier.issn1433-7851
dc.identifier.doi10.1002/anie.201511179
dc.identifier.doi10.1002/ange.201511179
dc.identifier.urihttp://hdl.handle.net/10754/623140
dc.description.abstractAn enantioselective addition of thiols and alcohols to aza-ortho-quinone methides, starting from diaryl methanols, was developed. The asymmetric additions occur under mild reaction conditions in the presence of chiral phosphoric acids and furnish the corresponding adducts with excellent yields and enantioselectivities.
dc.description.sponsorshipS.M. thanks the DFG (Deutsche Forschungsgemeinschaft) for financial support through the International Research Training Group SeleCa (IRTG 1628), H.-H.L. thanks the DAAD for a doctoral fellowship, M.S. thanks the JSPS (Japanese Society for the Promotion of Science) for financial support through the Japanese-German Graduate Externship.
dc.publisherWiley-Blackwell
dc.subjectBrønsted acids
dc.subjectCarbenium ions
dc.subjectMichael addition
dc.subjectortho-quinone methides
dc.subjectSubstitution
dc.titleAsymmetric Brønsted Acid Catalyzed Substitution of Diaryl Methanols with Thiols and Alcohols for the Synthesis of Chiral Thioethers and Ethers
dc.typeArticle
dc.contributor.departmentChemical Science Program
dc.contributor.departmentKAUST Catalysis Center (KCC)
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journalAngewandte Chemie International Edition
dc.contributor.institutionInstitute of Organic Chemistry; RWTH Aachen University; Landoltweg 1 52074 Aachen Germany
dc.contributor.institutionThe Institute of Scientific and Industrial Research (ISIR); Osaka University; Mihogaoka, Ibaraki-shi Osaka 567-0047 Japan
kaust.personRueping, Magnus
dc.date.published-online2016-03-08
dc.date.published-print2016-04-04


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