Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum
Name:
S1Fig.tif
Size:
2.243Mb
Format:
TIFF image
Description:
Supplemental files
Name:
S1Table.xlsx
Size:
17.81Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S2Fig.tif
Size:
528.4Kb
Format:
TIFF image
Description:
Supplemental files
Name:
S2Table.xlsx
Size:
292.5Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S3Fig.tif
Size:
251.0Kb
Format:
TIFF image
Description:
Supplemental files
Name:
S3Table.xlsx
Size:
24.29Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S4Fig.tif
Size:
449.5Kb
Format:
TIFF image
Description:
Supplemental files
Name:
S4Table.xlsx
Size:
22.26Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S5Fig.tif
Size:
482.8Kb
Format:
TIFF image
Description:
Supplemental files
Name:
S5Table.xlsx
Size:
20.18Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S6Fig.tif
Size:
1.295Mb
Format:
TIFF image
Description:
Supplemental files
Name:
S6Table.xlsx
Size:
81.10Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S7Fig.tif
Size:
10.32Mb
Format:
TIFF image
Description:
Supplemental files
Name:
S7Table.xlsx
Size:
537.0Kb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S8Fig.tif
Size:
1.224Mb
Format:
TIFF image
Description:
Supplemental files
Name:
S8Table.xlsx
Size:
4.089Mb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Name:
S9Fig.tif
Size:
958.4Kb
Format:
TIFF image
Description:
Supplemental files
Name:
S9Table.xlsx
Size:
5.525Mb
Format:
Microsoft Excel 2007
Description:
Supplemental files
Type
ArticleKAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionMarine Science Program
Red Sea Research Center (RSRC)
Date
2017-02-28Permanent link to this record
http://hdl.handle.net/10754/623074
Metadata
Show full item recordAbstract
RNA editing is a rare post-transcriptional event that provides cells with an additional level of gene expression regulation. It has been implicated in various processes including adaptation, viral defence and RNA interference; however, its potential role as a mechanism in acclimatization has just recently been recognised. Here, we show that RNA editing occurs in 1.6% of all nuclear-encoded genes of Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals. All base-substitution edit types were present, and statistically significant motifs were associated with three edit types. Strikingly, a subset of genes exhibited condition-specific editing patterns in response to different stressors that resulted in significant increases of non-synonymous changes. We posit that this previously unrecognised mechanism extends this organism’s capability to respond to stress beyond what is encoded by the genome. This in turn may provide further acclimatization capacity to these organisms, and by extension, their coral hosts.Citation
Liew YJ, Li Y, Baumgarten S, Voolstra CR, Aranda M (2017) Condition-specific RNA editing in the coral symbiont Symbiodinium microadriaticum. PLOS Genetics 13: e1006619. Available: http://dx.doi.org/10.1371/journal.pgen.1006619.Sponsors
Research reported in this publication was supported by funding from King Abdullah University of Science and Technology (KAUST). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We would like to thank Craig Michell for RNA-seq library construction, the KAUST Bioscience Core lab for library sequencing and Guoxin Cui for performing the differential expression analysis.Publisher
Public Library of Science (PLoS)Journal
PLOS Geneticsae974a485f413a2113503eed53cd6c53
10.1371/journal.pgen.1006619
Scopus Count
Except where otherwise noted, this item's license is described as This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.