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dc.contributor.authorNanda, Himansu Sekhar
dc.date.accessioned2017-02-26T06:34:21Z
dc.date.available2017-02-26T06:34:21Z
dc.date.issued2016-11-03
dc.identifier.citationNanda H (2016) Preparation and Biocompatible Surface Modification of Redox Altered Cerium Oxide Nanoparticle Promising for Nanobiology and Medicine. Bioengineering 3: 28. Available: http://dx.doi.org/10.3390/bioengineering3040028.
dc.identifier.issn2306-5354
dc.identifier.doi10.3390/bioengineering3040028
dc.identifier.urihttp://hdl.handle.net/10754/622925
dc.description.abstractThe biocompatible surface modification of metal oxide nanoparticles via surface functionalization technique has been used as an important tool in nanotechnology and medicine. In this report, we have prepared aqueous dispersible, trivalent metal ion (samarium)-doped cerium oxide nanoparticles (SmCNPs) as model redox altered CNPs of biological relevance. SmCNP surface modified with hydrophilic biocompatible (6-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-hexyl) triethoxysilane (MEEETES) were prepared using ammonia-induced ethylene glycol-assisted precipitation method and were characterized using a variety of complementary characterization techniques. The chemical interaction of functional moieties with the surface of doped nanoparticle was studied using powerful 13C cross polarization magic angle sample spinning nuclear magnetic resonance spectroscopy. The results demonstrated the production of the extremely small size MEEETES surface modified doped nanoparticles with significant reduction in aggregation compared to their unmodified state. Moreover, the functional moieties had strong chemical interaction with the surface of the doped nanoparticles. The biocompatible surface modification using MEEETES should also be extended to several other transition metal ion doped and co-doped CNPs for the production of aqueous dispersible redox altered CNPs that are promising for nanobiology and medicine.
dc.description.sponsorshipThe author would like to acknowledge the financial support from the King Abdullah University of Science and Technology (KAUST), Saudi Arabia.
dc.publisherMDPI AG
dc.relation.urlhttp://www.mdpi.com/2306-5354/3/4/28
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
dc.subjectcerium oxide nanoparticle
dc.subjectbiocompatible
dc.subjectsurface modification
dc.subjectaqueous dispersible
dc.subjectdoped and co-doped
dc.subjectnanobiology and medicine
dc.titlePreparation and Biocompatible Surface Modification of Redox Altered Cerium Oxide Nanoparticle Promising for Nanobiology and Medicine
dc.typeArticle
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.contributor.departmentWater Desalination and Reuse Research Center (WDRC)
dc.identifier.journalBioengineering
dc.eprint.versionPublisher's Version/PDF
dc.contributor.institutionSchool of Materials Science and Engineering, Nanyang Technological University, Singapore 639798, Singapore
kaust.personNanda, Himansu Sekhar
refterms.dateFOA2018-06-14T04:41:33Z


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