Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
AuthorsGallego Llorente, M.
Jones, E. R.
Arthur, K. W.
Arthur, J. W.
Curtis, M. C.
Stock, J. T.
Bradley, D. G.
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Integrative Systems Biology Lab
MetadataShow full item record
AbstractCharacterizing genetic diversity in Africa is a crucial step for most analyses reconstructing the evolutionary history of anatomically modern humans. However, historic migrations from Eurasia into Africa have affected many contemporary populations, confounding inferences. Here, we present a 12.5×coverage ancient genome of an Ethiopian male ("Mota") who lived approximately 4500 years ago. We use this genome to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4000 years earlier. The extent of this backflow was much greater than previously reported, reaching all the way to Central, West, and Southern Africa, affecting even populations such as Yoruba and Mbuti, previously thought to be relatively unadmixed, who harbor 6 to 7% Eurasian ancestry.
CitationLlorente MG, Jones ER, Eriksson A, Siska V, Arthur KW, et al. (2015) Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa. Science 350: 820–822. Available: http://dx.doi.org/10.1126/science.aad2879.
- Erratum for the Report "Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa" (previously titled "Ancient Ethiopian genome reveals extensive Eurasian admixture throughout the African continent") by M. Gallego Llorente, E. R. Jones, A. Eriksson, V. Siska, K. W. Arthur, J. W. Arthur, M. C. Curtis, J. T. Stock, M. Coltorti, P. Pieruccini, S. Stretton, F. Brock, T. Higham, Y. Park, M. Hofreiter, D. G. Bradley, J. Bhak, R. Pinhasi, A. Manica.
- Issue date: 2016 Feb 19
- Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations.
- Authors: Haber M, Mezzavilla M, Bergström A, Prado-Martinez J, Hallast P, Saif-Ali R, Al-Habori M, Dedoussis G, Zeggini E, Blue-Smith J, Wells RS, Xue Y, Zalloua PA, Tyler-Smith C
- Issue date: 2016 Dec 1
- Northeast African genomic variation shaped by the continuity of indigenous groups and Eurasian migrations.
- Authors: Hollfelder N, Schlebusch CM, Günther T, Babiker H, Hassan HY, Jakobsson M
- Issue date: 2017 Aug
- Tracing the route of modern humans out of Africa by using 225 human genome sequences from Ethiopians and Egyptians.
- Authors: Pagani L, Schiffels S, Gurdasani D, Danecek P, Scally A, Chen Y, Xue Y, Haber M, Ekong R, Oljira T, Mekonnen E, Luiselli D, Bradman N, Bekele E, Zalloua P, Durbin R, Kivisild T, Tyler-Smith C
- Issue date: 2015 Jun 4
- Human genetic data reveal contrasting demographic patterns between sedentary and nomadic populations that predate the emergence of farming.
- Authors: Aimé C, Laval G, Patin E, Verdu P, Ségurel L, Chaix R, Hegay T, Quintana-Murci L, Heyer E, Austerlitz F
- Issue date: 2013 Dec