Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa
AuthorsGallego Llorente, M.
Jones, E. R.
Arthur, K. W.
Arthur, J. W.
Curtis, M. C.
Stock, J. T.
Bradley, D. G.
KAUST DepartmentBiological and Environmental Sciences and Engineering (BESE) Division
Integrative Systems Biology Lab
Permanent link to this recordhttp://hdl.handle.net/10754/622517
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AbstractCharacterizing genetic diversity in Africa is a crucial step for most analyses reconstructing the evolutionary history of anatomically modern humans. However, historic migrations from Eurasia into Africa have affected many contemporary populations, confounding inferences. Here, we present a 12.5×coverage ancient genome of an Ethiopian male ("Mota") who lived approximately 4500 years ago. We use this genome to demonstrate that the Eurasian backflow into Africa came from a population closely related to Early Neolithic farmers, who had colonized Europe 4000 years earlier. The extent of this backflow was much greater than previously reported, reaching all the way to Central, West, and Southern Africa, affecting even populations such as Yoruba and Mbuti, previously thought to be relatively unadmixed, who harbor 6 to 7% Eurasian ancestry.
CitationLlorente MG, Jones ER, Eriksson A, Siska V, Arthur KW, et al. (2015) Ancient Ethiopian genome reveals extensive Eurasian admixture in Eastern Africa. Science 350: 820–822. Available: http://dx.doi.org/10.1126/science.aad2879.
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