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dc.contributor.authorCastro, David
dc.contributor.authorConchouso Gonzalez, David
dc.contributor.authorCarreno, Armando Arpys Arevalo
dc.contributor.authorFoulds, Ian G.
dc.date.accessioned2017-01-02T09:55:27Z
dc.date.available2017-01-02T09:55:27Z
dc.date.issued2016-12-19
dc.identifier.citationCastro D, Conchouso D, Arevalo A, Foulds IG (2016) A study of the incubation of microbead agglutination assays in a microfluidic system. 2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). Available: http://dx.doi.org/10.1109/NEMS.2016.7758266.
dc.identifier.doi10.1109/NEMS.2016.7758266
dc.identifier.urihttp://hdl.handle.net/10754/622509
dc.description.abstractThis work reports on a quantitative study of the incubation of a microbead-based agglutination assay inside a microfluidic system. In this system, a droplet (1.25µL) consisting of a mixture of functionalized microbeads and analyte is flowed through a 0.51mm internal diameter silicone tube. Hydrodynamic forces alone produce a very efficient mixing of the beads within the droplet. We tested the agglutination at different speeds and show a robust response at the higher range of speeds (150 – 200µL/min), while also reaching a completion in the agglutination process. At these velocities, a length of 180cm is shown to be sufficient to confidently measure the agglutination assay, which takes between 2.5 – 3 minutes. This high throughput quantification method has the potential of accelerating the measurements of various types of biomarkers, which can greatly benefit the fields of biology and medicine.
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)
dc.relation.urlhttp://ieeexplore.ieee.org/document/7758266/
dc.titleA study of the incubation of microbead agglutination assays in a microfluidic system
dc.typeConference Paper
dc.contributor.departmentComputer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
dc.contributor.departmentElectrical Engineering Program
dc.contributor.departmentMechanical Engineering Program
dc.contributor.departmentPhysical Science and Engineering (PSE) Division
dc.identifier.journal2016 IEEE 11th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)
dc.contributor.institutionUniversity of British Columbia (UBC). Kelenowa, Canada
kaust.personCastro, David
kaust.personConchouso Gonzalez, David
kaust.personCarreno, Armando Arpys Arevalo
kaust.personFoulds, Ian G.
dc.date.published-online2016-12-19
dc.date.published-print2016-04


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