Cholesteryl ester transfer protein (cetp) inhibition in the treatment of cancer

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Type
Patent
Patent Status
Published Application
Authors
Kaur, Mandeep
Esau, Luke E.
Sagar, Sunii
Assignee
King Abdullah University Of Science & Technology
KAUST Department
Computational Bioscience Research Center (CBRC)
Date
2016-09-01
Submitted Date
2015-02-24
Permanent link to this record
http://hdl.handle.net/10754/621914

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Abstract
In one embodiment, the invention provides methods of treatment which use therapeutically effective amounts of Choleste ryl Ester Transfer Protein (CETP) inhibitors to treat a variety of cancers. In certain embodiments, the inhibitor is a CETP-inhibiting small molecule, CETP-inhibiting antisense oligonucleotide, CETP-inhibiting siRNA or a CETP- inhibiting antibody. Related pharmaceutical compositions, kits, diagnostics and screens are also provided.
Application Number
WO 2016135633 A1
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http://www.google.com/patents/WO2016135633A1
http://worldwide.espacenet.com/publicationDetails/biblio?CC=WO&NR=2016135633A1&KC=A1&FT=D
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