Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation
Type
ArticleKAUST Department
Chemical Science ProgramKAUST Catalysis Center (KCC)
Physical Science and Engineering (PSE) Division
Date
2016-06-13Online Publication Date
2016-06-13Print Publication Date
2016-07Permanent link to this record
http://hdl.handle.net/10754/621676
Metadata
Show full item recordAbstract
A new and efficient nickel-catalyzed alkylation of CAr-O electrophiles with B-alkyl-9-BBNs is described. The transformation is characterized by its functional group tolerance and provides a practical and versatile access to various Csp2-Csp3 bonds through Csp2-O substitution, without the restriction of β-hydride elimination. Moreover, the advantage of the newly developed method was demonstrated in a selective and sequential C-O bond activation process. © 2016 American Chemical Society.Citation
Guo L, Hsiao C-C, Yue H, Liu X, Rueping M (2016) Nickel-Catalyzed C sp2 –C sp3 Cross-Coupling via C–O Bond Activation . ACS Catalysis 6: 4438–4442. Available: http://dx.doi.org/10.1021/acscatal.6b00801.Sponsors
L.G., H.Y., and X.L. gratefully acknowledge the China Scholarship Council. C.-C.H. gratefully acknowledges DAAD for fellowship.Publisher
American Chemical Society (ACS)Journal
ACS Catalysisae974a485f413a2113503eed53cd6c53
10.1021/acscatal.6b00801