• Login
    View Item 
    •   Home
    • Research
    • Articles
    • View Item
    •   Home
    • Research
    • Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Electrical impedance spectroscopy (EIS)-based evaluation of biological tissue phantoms to study multifrequency electrical impedance tomography (Mf-EIT) systems

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Type
    Article
    Authors
    Bera, Tushar Kanti
    Nagaraju, J.
    Lubineau, Gilles cc
    KAUST Department
    Composite and Heterogeneous Material Analysis and Simulation Laboratory (COHMAS)
    Mechanical Engineering Program
    Physical Science and Engineering (PSE) Division
    Date
    2016-03-14
    Online Publication Date
    2016-03-14
    Print Publication Date
    2016-11
    Permanent link to this record
    http://hdl.handle.net/10754/621541
    
    Metadata
    Show full item record
    Abstract
    Abstract: Electrical impedance tomography (EIT) phantoms are essential for the calibration, comparison and evaluation of the EIT systems. In EIT, the practical phantoms are typically developed based on inhomogeneities surrounded by a homogeneous background to simulate a suitable conductivity contrast. In multifrequency EIT (Mf-EIT) evaluation, the phantoms must be developed with the materials which have recognizable or distinguishable impedance variations over a wide range of frequencies. In this direction the impedance responses of the saline solution (background) and a number vegetable and fruit tissues (inhomogeneities) are studied with electrical impedance spectroscopy (EIS) and the frequency responses of bioelectrical impedance and conductivity are analyzed. A number of practical phantoms with different tissue inhomogeneities and different inhomogeneity configurations are developed and the multifrequency impedance imaging is studied with the Mf-EIT system to evaluate the phantoms. The conductivity of the vegetable inhomogeneities reconstructed from the EIT imaging is compared with the conductivity values obtained from the EIS studies. Experimental results obtained from multifrequency EIT reconstruction demonstrate that the electrical impedance of all the biological tissues inhomogenity decreases with frequency. The potato tissue phantom produces better impedance image in high frequency ranges compared to the cucumber phantom, because the cucumber impedance at high frequency becomes lesser than that of the potato at the same frequency range. Graphical Abstract: [Figure not available: see fulltext.] © 2016 The Visualization Society of Japan
    Citation
    Bera TK, Nagaraju J, Lubineau G (2016) Electrical impedance spectroscopy (EIS)-based evaluation of biological tissue phantoms to study multifrequency electrical impedance tomography (Mf-EIT) systems. Journal of Visualization 19: 691–713. Available: http://dx.doi.org/10.1007/s12650-016-0351-0.
    Publisher
    Springer Nature
    Journal
    Journal of Visualization
    DOI
    10.1007/s12650-016-0351-0
    ae974a485f413a2113503eed53cd6c53
    10.1007/s12650-016-0351-0
    Scopus Count
    Collections
    Articles; Physical Science and Engineering (PSE) Division; Mechanical Engineering Program

    entitlement

     

    Related items

    Showing items related by title, author, creator and subject.

    • Thumbnail

      Discontinuous Galerkin Time-Domain Modeling of Graphene Nano-Ribbon Incorporating the Spatial Dispersion Effects

      Li, Ping; Jiang, Li Jun; Bagci, Hakan (IEEE Transactions on Antennas and Propagation, Institute of Electrical and Electronics Engineers (IEEE), 2018-04-13) [Article]
      It is well known that graphene demonstrates spatial dispersion properties, i.e., its conductivity is nonlocal and a function of spectral wave number (momentum operator) q. In this paper, to account for effects of spatial dispersion on transmission of high speed signals along graphene nano-ribbon (GNR) interconnects, a discontinuous Galerkin time-domain (DGTD) algorithm is proposed. The atomically-thick GNR is modeled using a nonlocal transparent surface impedance boundary condition (SIBC) incorporated into the DGTD scheme. Since the conductivity is a complicated function of q (and one cannot find an analytical Fourier transform pair between q and spatial differential operators), an exact time domain SIBC model cannot be derived. To overcome this problem, the conductivity is approximated by its Taylor series in spectral domain under low-q assumption. This approach permits expressing the time domain SIBC in the form of a second-order partial differential equation (PDE) in current density and electric field intensity. To permit easy incorporation of this PDE with the DGTD algorithm, three auxiliary variables, which degenerate the second-order (temporal and spatial) differential operators to first-order ones, are introduced. Regarding to the temporal dispersion effects, the auxiliary differential equation (ADE) method is utilized to eliminates the expensive temporal convolutions. To demonstrate the applicability of the proposed scheme, numerical results, which involve characterization of spatial dispersion effects on the transfer impedance matrix of GNR interconnects, are presented.
    • Thumbnail

      Detection of ischemic changes in the vascular endothelial cell layer by using microelectrochemical impedance spectroscopy

      Cha, Jung-Joon; Kim, Jinhwan; Yun, Joho; Park, Yangkyu; Lee, Jong-Hyun (Medical Engineering & Physics, Elsevier BV, 2018-10-11) [Article]
      Endothelial cells have many important roles in the cardiovascular system, such as controlling vasomotor actions and hemostasis. In the event of endothelial cell dysfunction, the risk of cardiovascular disease increases. Therefore, the objective of this study was to investigate the early detection and diagnosis of endothelial cell dysfunction. Injury and restoration in vascular endothelial cells exposed to ischemic stress may affect changes in the electrical impedance. We measured the status of the endothelial cell layer by using microelectrochemical impedance spectroscopy. We used cultured rat primary vascular endothelial cells to measure the electrical impedance under different conditions (control, ischemia, and recovery). Our results revealed that the electrical impedance in vascular endothelial cells under different conditions has quantitatively distinct values. At the optimal frequency, the real parts (Z) of the impedances for the control group, ischemic group, and recovery group were 0.54 kΩ 0.28 kΩ and 0.58 kΩ respectively. The imaginary parts (Z) of the impedances for each group were − 0.19 kΩ − 0.12 kΩ and − 0.18 kΩ respectively. The values for both the recovery group and control group were similar. In this context, electrical impedance measurement could be considered as possible method for direct detection of vascular endothelial cell injury in ischemic conditions. To the best of our knowledge, this study is the first attempt to measure changes in the electrical impedance of vascular endothelial cells during ischemic damage and the recovery processes.
    • Thumbnail

      Label-free, electrochemical detection of methicillin-resistant staphylococcus aureus DNA with reduced graphene oxide-modified electrodes

      Wang, Zhijuan; Zhang, Juan; Chen, Peng; Zhou, Xiaozhu; Yang, Yanli; Wu, Shixin; Niu, Li; Han, Yu; Wang, Lianhui; Chen, Peng; Boey, Freddy; Zhang, Qichun; Liedberg, Bo Gunnar; Zhang, Hua (Biosensors and Bioelectronics, Elsevier BV, 2011-05) [Article]
      Reduced graphene oxide (rGO)-modified glassy carbon electrode is used to detect the methicillin-resistant Staphylococcus aureus (MRSA) DNA by using electrochemical impedance spectroscopy. Our experiments confirm that ssDNA, before and after hybridization with target DNA, are successfully anchored on the rGO surface. After the probe DNA, pre-adsorbed on rGO electrode, hybridizes with target DNA, the measured impedance increases dramatically. It provides a new method to detect DNA with high sensitivity (10-13M, i.e., 100 fM) and selectivity. © 2011 Elsevier B.V.
    DSpace software copyright © 2002-2022  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.