Chloroplasts activity and PAP-signaling regulate programmed cell death in Arabidopsis
Type
ArticleAuthors
Bruggeman, QuentinMazubert, Christelle
Prunier, Florence
Lugan, Raphael
Chan, Kai Xun
Phua, Su Yin
Pogson, Barry J.
Krieger-Liszkay, Anja
Delarue, Marianne
Benhamed, Moussa

Bergounioux, Catherine
Raynaud, Cécile
KAUST Department
Biological and Environmental Sciences and Engineering (BESE) DivisionDesert Agriculture Initiative
Plant Science
Plant Science Program
Date
2016-01-08Online Publication Date
2016-01-08Print Publication Date
2016-03Permanent link to this record
http://hdl.handle.net/10754/621468
Metadata
Show full item recordAbstract
Programmed cell death (PCD) is a crucial process both for plant development and responses to biotic and abiotic stress. There is accumulating evidence that chloroplasts may play a central role during plant PCD as for mitochondria in animal cells, but it is still unclear whether they participate in PCD onset, execution, or both. To tackle this question, we have analyzed the contribution of chloroplast function to the cell death phenotype of the myoinositol phosphate synthase1 (mips1) mutant that forms spontaneous lesions in a light-dependent manner. We show that photosynthetically active chloroplasts are required for PCD to occur in mips1, but this process is independent of the redox state of the chloroplast. Systematic genetic analyses with retrograde signaling mutants reveal that 3’-phosphoadenosine 5’-phosphate, a chloroplast retrograde signal that modulates nuclear gene expression in response to stress, can inhibit cell death and compromises plant innate immunity via inhibition of the RNA-processing 5’-3’ exoribonucleases. Our results provide evidence for the role of chloroplast-derived signal and RNA metabolism in the control of cell death and biotic stress response. © 2016 American Society of Plant Biologists. All Rights Reserved.Citation
Bruggeman Q, Mazubert C, Prunier F, Lugan R, Chan KX, et al. (2016) Chloroplasts activity and PAP-signaling regulate programmed cell death in Arabidopsis. Plant Physiol: pp.01872.2015. Available: http://dx.doi.org/10.1104/pp.15.01872.Sponsors
This work was supported by the Agence Nationale de la Recherche (grant nos. ANR 2010 JCJC1207 01 and MAPK-IPS ANR-2010-BLAN-1613-02).Journal
Plant PhysiologyPubMed ID
26747283ae974a485f413a2113503eed53cd6c53
10.1104/pp.15.01872
Scopus Count
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