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    Sensors and Instrumentation towards early detection of osteoporosis

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    Type
    Conference Paper
    Authors
    Afsarimanesh, Nasrin
    Mukhopadhyay, Subhas C
    Kruger, Marlena
    Yu, Pak-Lam
    Kosel, Jürgen cc
    KAUST Department
    Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division
    Electrical Engineering Program
    Date
    2016-07-27
    Online Publication Date
    2016-07-27
    Print Publication Date
    2016-05
    Permanent link to this record
    http://hdl.handle.net/10754/621291
    
    Metadata
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    Abstract
    A label-free non-invasive sensing system for detection of C-terminal telopeptide of type-I collagen (CTX-I) has been developed in order to detect bone loss at an early stage, by Electrochemical Impedance Spectroscopy (EIS). A planar interdigital sensor was functionalized by immobilizing streptavidin agarose on the sensing area of the sensor to introduce selectivity for the antigen-antibody solution. Different concentrations of CTX-I were tested using the functionalized sensing surface to capture the target molecule. Preliminary results are provided in the paper assisted with the respective equivalent circuit of the working technology on the sensor using Complex Non-linear Least Square (CNLS). The results are encouraging and will be used to develop a complete system for commercialization complementing the existing systems. © 2016 IEEE.
    Citation
    Afsarimanesh N, Mukhopadhyay SC, Kruger M, Yu P-L, Kosel J (2016) Sensors and Instrumentation towards early detection of osteoporosis. 2016 IEEE International Instrumentation and Measurement Technology Conference Proceedings. Available: http://dx.doi.org/10.1109/I2MTC.2016.7520573.
    Publisher
    Institute of Electrical and Electronics Engineers (IEEE)
    Journal
    2016 IEEE International Instrumentation and Measurement Technology Conference Proceedings
    Conference/Event name
    2016 IEEE International Instrumentation and Measurement Technology Conference, I2MTC 2016
    DOI
    10.1109/I2MTC.2016.7520573
    ae974a485f413a2113503eed53cd6c53
    10.1109/I2MTC.2016.7520573
    Scopus Count
    Collections
    Conference Papers; Electrical and Computer Engineering Program; Computer, Electrical and Mathematical Science and Engineering (CEMSE) Division

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