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dc.contributor.authorLin, Ran
dc.contributor.authorChang, Donald C.
dc.contributor.authorLee, Yi-Kuen
dc.date.accessioned2016-02-28T08:00:17Z
dc.date.available2016-02-28T08:00:17Z
dc.date.issued2012-03
dc.identifier.citationLin R, Chang DC, Lee Y-K (2012) The effect of Cytochalasin D on F-Actin behavior of single-cell electroendocytosis using multi-chamber micro cell chip. 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). Available: http://dx.doi.org/10.1109/nems.2012.6196744.
dc.identifier.isbn9781467311243
dc.identifier.doi10.1109/nems.2012.6196744
dc.identifier.urihttp://hdl.handle.net/10754/600264
dc.description.abstractElectroendocytosis (EED) is a pulsed-electric-field (PEF) induced endocytosis, facilitating cells uptake molecules through nanometer-sized EED vesicles. We herein investigate the effect of a chemical inhibitor, Cytochalasin D (CD) on the actin-filaments (F-Actin) behavior of single-cell EED. The CD concentration (C CD) can control the depolymerization of F-actin. A multi-chamber micro cell chip was fabricated to study the EED under different conditions. Large-scale single-cell data demonstrated EED highly depends on both electric field and C CD. © 2012 IEEE.
dc.description.sponsorshipThe research was sponsored by a grant from Hong Kong Research Grants Council (Grant Ref. No. 615907) and by an award from the King Abdullah University of Science and Technology (KAUST Award No. SA-C0040/UK-COOI6).
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)
dc.subjectActin filament
dc.subjectCytochalasin D
dc.subjectElectroendocytosis
dc.subjectMicro Cell Chip
dc.titleThe effect of Cytochalasin D on F-Actin behavior of single-cell electroendocytosis using multi-chamber micro cell chip
dc.typeConference Paper
dc.identifier.journal2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)
dc.conference.date5 March 2012 through 8 March 2012
dc.conference.name7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
dc.conference.locationKyoto
dc.contributor.institutionBioengineering Graduate Program, HKUST, Kowloon, Hong Kong
dc.contributor.institutionDept. of Mechanical Engineering, HKUST, Kowloon, Hong Kong
dc.contributor.institutionDivision of Life Science, HKUST, Kowloon, Hong Kong
kaust.personLee, Yi-Kuen
kaust.grant.numberSA-C0040
kaust.grant.numberUK-COOI6
kaust.grant.fundedcenterKAUST-HKUST Micro/Nanofluidic Joint Laboratory


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