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    The effect of Cytochalasin D on F-Actin behavior of single-cell electroendocytosis using multi-chamber micro cell chip

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    Type
    Conference Paper
    Authors
    Lin, Ran
    Chang, Donald C.
    Lee, Yi-Kuen cc
    KAUST Grant Number
    SA-C0040
    UK-COOI6
    Date
    2012-03
    Permanent link to this record
    http://hdl.handle.net/10754/600264
    
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    Abstract
    Electroendocytosis (EED) is a pulsed-electric-field (PEF) induced endocytosis, facilitating cells uptake molecules through nanometer-sized EED vesicles. We herein investigate the effect of a chemical inhibitor, Cytochalasin D (CD) on the actin-filaments (F-Actin) behavior of single-cell EED. The CD concentration (C CD) can control the depolymerization of F-actin. A multi-chamber micro cell chip was fabricated to study the EED under different conditions. Large-scale single-cell data demonstrated EED highly depends on both electric field and C CD. © 2012 IEEE.
    Citation
    Lin R, Chang DC, Lee Y-K (2012) The effect of Cytochalasin D on F-Actin behavior of single-cell electroendocytosis using multi-chamber micro cell chip. 2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). Available: http://dx.doi.org/10.1109/nems.2012.6196744.
    Sponsors
    The research was sponsored by a grant from Hong Kong Research Grants Council (Grant Ref. No. 615907) and by an award from the King Abdullah University of Science and Technology (KAUST Award No. SA-C0040/UK-COOI6).
    Publisher
    Institute of Electrical and Electronics Engineers (IEEE)
    Journal
    2012 7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)
    Conference/Event name
    7th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2012
    ISBN
    9781467311243
    DOI
    10.1109/nems.2012.6196744
    ae974a485f413a2113503eed53cd6c53
    10.1109/nems.2012.6196744
    Scopus Count
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