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    Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis

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    Type
    Article
    Authors
    Li, Ming cc
    Li, Shunbo
    Cao, Wenbin
    Li, Weihua
    Wen, Weijia
    Alici, Gursel
    Date
    2012-07-26
    Permanent link to this record
    http://hdl.handle.net/10754/600245
    
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    Abstract
    We present a waved microchannel for continuous focusing of microparticles and cells using negative direct current (dc) dielectrophoresis. The waved channel is composed of consecutive s-shaped curved channels in series to generate an electric field gradient required for the dielectrophoretic effect. When particles move electrokinetically through the channel, the experienced negative dielectrophoretic forces alternate directions within two adjacent semicircular microchannels, leading to a focused continuous-flow stream along the channel centerline. Both the experimentally observed and numerically simulated results of the focusing performance are reported, which coincide acceptably in proportion to the specified dimensions (i.e. inlet and outlet of the waved channel). How the applied electric field, particle size and medium concentration affect the performance was studied by focusing polystyrene microparticles of varying sizes. As an application in the field of biology, the focusing of yeast cells in the waved mcirochannel was tested. This waved microchannel shows a great potential for microflow cytometry applications and is expected to be widely used before different processing steps in lab-on-A-chip devices with integrated functions. © 2012 IOP Publishing Ltd.
    Citation
    Li M, Li S, Cao W, Li W, Wen W, et al. (2012) Continuous particle focusing in a waved microchannel using negative dc dielectrophoresis. Journal of Micromechanics and Microengineering 22: 095001. Available: http://dx.doi.org/10.1088/0960-1317/22/9/095001.
    Sponsors
    The authors wish to thank the University of Wollongong funding support to promote the collaboration with The Hong Kong University of Science and Technology through an international linkage scheme.
    Publisher
    IOP Publishing
    Journal
    Journal of Micromechanics and Microengineering
    ISSN
    0960-1317
    1361-6439
    DOI
    10.1088/0960-1317/22/9/095001
    ae974a485f413a2113503eed53cd6c53
    10.1088/0960-1317/22/9/095001
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