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dc.contributor.authorSun, Jian Fan
dc.contributor.authorHan, Zhuang
dc.contributor.authorZhou, Xue Feng
dc.contributor.authorYang, Bin
dc.contributor.authorLin, Xiuping
dc.contributor.authorLiu, Juan
dc.contributor.authorPeng, Yan
dc.contributor.authorYang, Xian Wen
dc.contributor.authorLiu, Yonghong
dc.date.accessioned2016-02-28T07:59:26Z
dc.date.available2016-02-28T07:59:26Z
dc.date.issued2013-01
dc.identifier.citationSun J-F, Han Z, Zhou X-F, Yang B, Lin X, et al. (2013) Antifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea. Tetrahedron 69: 871–880. Available: http://dx.doi.org/10.1016/j.tet.2012.10.102.
dc.identifier.issn0040-4020
dc.identifier.doi10.1016/j.tet.2012.10.102
dc.identifier.urihttp://hdl.handle.net/10754/600225
dc.description.abstractOur continued investigation on the South China Sea gorgonian Dichotella gemmacea led to the isolation of 16 new briarane-type diterpenoids, dichotellides F-U (1-16), along with 18 known analogues (17-34). Their structures were determined by MS, 1D and 2D NMR spectra analyses and by comparison with those reported in literature. The absolute configuration of 15 was confirmed by single-crystal X-ray diffraction data. The antifouling test showed that compounds 3, 4, 6-11, 16, and 23 had potent antifouling activities at nontoxic concentrations with EC50 values of 4.1, 1.82, 6.3, 7.6, 4.6, 1.2, 5.6, 0.79, 2.0, and 0.2 μg/mL, respectively. © 2012 Elsevier Ltd. All rights reserved.
dc.description.sponsorshipThis study was supported by the National Basic Research Program of China (973 Program, Nos. 2010CB833800 and 2011CB915503), the National High Technology Research and Development Program (863 Program, 2012AA092104), Knowledge Innovation Program of Chinese Academy of Science (KSCX2-YW-G-073 and KSCX2-EW-G-12B), and National Natural Science Foundation of China (Nos. 30973679, 20902094, 21172230, 41176148, 21002110).Guangdong Province-CAS Joint Research Program (2011B0 90300023), Guangdong Province Marine and Fishery Special Project for Science and Technology Popularization (A201101F03), the start-up grant from Jiangsu University (11JDG1147).
dc.publisherElsevier BV
dc.subjectAntifouling agents
dc.subjectDichotella gemmacea
dc.subjectDiterpenoids
dc.subjectNatural products
dc.subjectNontoxic
dc.subjectStructure elucidation
dc.titleAntifouling briarane type diterpenoids from South China Sea gorgonians Dichotella gemmacea
dc.typeArticle
dc.identifier.journalTetrahedron
dc.contributor.institutionKey Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
dc.contributor.institutionSchool of Environment, Jiangsu University, Zhenjiang 212013, China
kaust.personHan, Zhuang
kaust.grant.programKAUST Global Partnership Program


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