Type
ArticleKAUST Grant Number
KUK-CI013-04Date
2012-05-16Online Publication Date
2012-05-16Print Publication Date
2012-08-22Permanent link to this record
http://hdl.handle.net/10754/600195
Metadata
Show full item recordAbstract
Disease control by managers is a crucial response to emerging wildlife epidemics, yet the means of control may be limited by the method of disease transmission. In particular, it is widely held that population reduction, while effective for controlling diseases that are subject to density-dependent (DD) transmission, is ineffective for controlling diseases that are subject to frequency-dependent (FD) transmission. We investigate control for horizontally transmitted diseases with FD transmission where the control is via culling or harvest that is non-selective with respect to infection and the population can compensate through DD recruitment or survival. Using a mathematical model, we show that culling or harvesting can eradicate the disease, even when transmission dynamics are FD. Eradication can be achieved under FD transmission when DD birth or recruitment induces compensatory growth of new, healthy individuals, which has the net effect of reducing disease prevalence by dilution. We also show that if harvest is used simultaneously with vaccination, and there is high enough transmission coefficient, application of both controls may be less efficient than vaccination alone. We illustrate the effects of these control approaches on disease prevalence for chronic wasting disease in deer where the disease is transmitted directly among deer and through the environment.Citation
Potapov A, Merrill E, Lewis MA (2012) Wildlife disease elimination and density dependence. Proceedings of the Royal Society B: Biological Sciences 279: 3139–3145. Available: http://dx.doi.org/10.1098/rspb.2012.0520.Sponsors
This work has been supported by Alberta Prion Research Institute and Alberta Innovation through grants (E. Merrill: RES0004230), Natural Sciences and Engineering Research Council of Canada Discovery Grants (E. M., M. A. L.) Canada Research Chair (M. A. L.), NSERC Accelerator Grant (M. A. L.) and Research Fellowship from Oxford Centre for Collaborative and Applied Mathematics supported by Award no. KUK-CI013-04 made by King Abdullah University of Science and Technology (KAUST) (M. A. L.). We thank reviewers for helpful suggestions.Publisher
The Royal SocietyPubMed ID
22593103PubMed Central ID
PMC3385729ae974a485f413a2113503eed53cd6c53
10.1098/rspb.2012.0520
Scopus Count
Collections
Publications Acknowledging KAUST SupportRelated articles
- Modeling seasonal behavior changes and disease transmission with application to chronic wasting disease.
- Authors: Oraby T, Vasilyeva O, Krewski D, Lutscher F
- Issue date: 2014 Jan 7
- Modeling routes of chronic wasting disease transmission: environmental prion persistence promotes deer population decline and extinction.
- Authors: Almberg ES, Cross PC, Johnson CJ, Heisey DM, Richards BJ
- Issue date: 2011
- Spatial epidemiology of chronic wasting disease in Wisconsin white-tailed deer.
- Authors: Joly DO, Samuel MD, Langenberg JA, Blanchong JA, Batha CA, Rolley RE, Keane DP, Ribic CA
- Issue date: 2006 Jul
- Host culling as an adaptive management tool for chronic wasting disease in white-tailed deer: a modelling study.
- Authors: Wasserberg G, Osnas EE, Rolley RE, Samuel MD
- Issue date: 2009 Apr
- The role of predation in disease control: a comparison of selective and nonselective removal on prion disease dynamics in deer.
- Authors: Wild MA, Hobbs NT, Graham MS, Miller MW
- Issue date: 2011 Jan