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dc.contributor.authorAydemir, E.
dc.contributor.authorBreward, C. J. W.
dc.contributor.authorWitelski, T. P.
dc.date.accessioned2016-02-28T06:32:08Z
dc.date.available2016-02-28T06:32:08Z
dc.date.issued2010-06-17
dc.identifier.citationAydemir E, Breward CJW, Witelski TP (2010) The Effect of Polar Lipids on Tear Film Dynamics. Bull Math Biol 73: 1171–1201. Available: http://dx.doi.org/10.1007/s11538-010-9555-y.
dc.identifier.issn0092-8240
dc.identifier.issn1522-9602
dc.identifier.pmid20556530
dc.identifier.doi10.1007/s11538-010-9555-y
dc.identifier.urihttp://hdl.handle.net/10754/599905
dc.description.abstractIn this paper, we present a mathematical model describing the effect of polar lipids, excreted by glands in the eyelid and present on the surface of the tear film, on the evolution of a pre-corneal tear film. We aim to explain the interesting experimentally observed phenomenon that the tear film continues to move upward even after the upper eyelid has become stationary. The polar lipid is an insoluble surface species that locally alters the surface tension of the tear film. In the lubrication limit, the model reduces to two coupled non-linear partial differential equations for the film thickness and the concentration of lipid. We solve the system numerically and observe that increasing the concentration of the lipid increases the flow of liquid up the eye. We further exploit the size of the parameters in the problem to explain the initial evolution of the system. © 2010 Society for Mathematical Biology.
dc.description.sponsorshipThe authors are particularly grateful for extensive dialogue with Prof. Colin Please,useful comments by Dr. Jim Oliver, and for the support and insight provided by their experimental collab-orators, Prof. Anthony Bron and Dr. John Tiffany. This work was partly funded by an EPSRC-funded MScstudentship, is also partially based on work supported by award number KUK-C1-013-04 made by KingAbdullah University of Science and Technology and by NSF DMS CAREER grant 0239125.
dc.publisherSpringer Nature
dc.subjectBlinking
dc.subjectFluid mechanics
dc.subjectLipids
dc.subjectLubrication theory
dc.subjectTear films
dc.titleThe Effect of Polar Lipids on Tear Film Dynamics
dc.typeArticle
dc.identifier.journalBulletin of Mathematical Biology
dc.contributor.institutionUniversity of Oxford, Oxford, United Kingdom
dc.contributor.institutionDuke University, Durham, United States
kaust.grant.numberKUK-C1-013-04
dc.date.published-online2010-06-17
dc.date.published-print2011-06


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