• Login
    View Item 
    •   Home
    • Office of Sponsored Research (OSR)
    • KAUST Funded Research
    • Publications Acknowledging KAUST Support
    • View Item
    •   Home
    • Office of Sponsored Research (OSR)
    • KAUST Funded Research
    • Publications Acknowledging KAUST Support
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of KAUSTCommunitiesIssue DateSubmit DateThis CollectionIssue DateSubmit Date

    My Account

    Login

    Quick Links

    Open Access PolicyORCID LibguideTheses and Dissertations LibguideSubmit an Item

    Statistics

    Display statistics

    Refillable and magnetically actuated drug delivery system using pear-shaped viscoelastic membrane

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Type
    Article
    Authors
    So, Hongyun cc
    Seo, Young Ho
    Pisano, Albert P.
    Date
    2014-07
    Permanent link to this record
    http://hdl.handle.net/10754/599481
    
    Metadata
    Show full item record
    Abstract
    We report a refillable and valveless drug delivery device actuated by an external magnetic field for on-demand drug release to treat localized diseases. The device features a pear-shaped viscoelastic magnetic membrane inducing asymmetrical deflection and consecutive touchdown motion to the bottom of the dome-shaped drug reservoir in response to a magnetic field, thus achieving controlled discharge of the drug. Maximum drug release with 18 ± 1.5 μg per actuation was achieved under a 500 mT magnetic flux density, and various controlled drug doses were investigated with the combination of the number of accumulated actuations and the strength of the magnetic field.
    Citation
    So H, Seo YH, Pisano AP (2014) Refillable and magnetically actuated drug delivery system using pear-shaped viscoelastic membrane. Biomicrofluidics 8: 044119. Available: http://dx.doi.org/10.1063/1.4893912.
    Sponsors
    This work was supported by the KAUST Global Collaborative Research grant under the Academic Excellence Alliance program. The authors also thank the UC Berkeley Marvell Nanolab and Biomolecular Nanotechnology Center where all devices were fabricated.
    Publisher
    AIP Publishing
    Journal
    Biomicrofluidics
    DOI
    10.1063/1.4893912
    PubMed ID
    25379104
    PubMed Central ID
    PMC4189303
    ae974a485f413a2113503eed53cd6c53
    10.1063/1.4893912
    Scopus Count
    Collections
    Publications Acknowledging KAUST Support

    entitlement

    Related articles

    • A magnetically controlled MEMS device for drug delivery: design, fabrication, and testing.
    • Authors: Pirmoradi FN, Jackson JK, Burt HM, Chiao M
    • Issue date: 2011 Sep 21
    • Design and fabrication of a magnetically actuated non-invasive reusable drug delivery device.
    • Authors: Dsa J, Goswami M, Singh BR, Bhatt N, Sharma P, Chauhan MK
    • Issue date: 2018 Jul
    • Performance Evaluation of a Magnetically Actuated Capsule Microrobotic System for Medical Applications.
    • Authors: Fu Q, Zhang S, Guo S, Guo J
    • Issue date: 2018 Dec 4
    • Implantable small device enabled with magnetic actuation for on-demand and pulsatile drug delivery.
    • Authors: Lee SH, Kim BH, Park CG, Lee C, Lim BY, Choy YB
    • Issue date: 2018 Sep 28
    • On-demand controlled release of docetaxel from a battery-less MEMS drug delivery device.
    • Authors: Pirmoradi FN, Jackson JK, Burt HM, Chiao M
    • Issue date: 2011 Aug 21
    DSpace software copyright © 2002-2023  DuraSpace
    Quick Guide | Contact Us | KAUST University Library
    Open Repository is a service hosted by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items. For anonymous users the allowed maximum amount is 50 search results.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.