Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics
KAUST Grant NumberKUK-F1-029-32
MetadataShow full item record
AbstractSynthetic methods in polymer chemistry have evolved tremendously during the last decade. Nowadays more and more attention is devoted to the application of those tools in the development of the next generation of nanomedicines. Nevertheless, poly(ethylene glycol) (PEG) remains the most frequently used polymer for biomedical applications. In this review, we try to summarize recent efforts and developments in controlled polymerisation techniques that may allow alternatives to PEG based systems and can be used to improve the properties of future polymer therapeutics. © 2011 The Royal Society of Chemistry.
CitationBarz M, Luxenhofer R, Zentel R, Vicent MJ (2011) Overcoming the PEG-addiction: well-defined alternatives to PEG, from structure–property relationships to better defined therapeutics. Polymer Chemistry 2: 1900. Available: http://dx.doi.org/10.1039/c0py00406e.
SponsorsR.L. gratefully acknowledges support by the King Abdullah University of Science and Technology, KAUST (award no. KUK-F1-029-32) and ongoing support by Prof. R. Jordan. M.B. would like to thank the graduate school of excellence MAINZ, COMATT, IMPRS, the Spanish Ministry Grant (CTQ2007-606019), European Commission FP7-Health program (proposal n. 241919, LIVIMODE) and particularly the cluster of excellence SAMT of Rhineland-Palatina for support and funding.
PublisherRoyal Society of Chemistry (RSC)