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    Osmotic actuation for microfluidic components in point-of-care applications

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    Type
    Conference Paper
    Authors
    Chen, Yu-Chih
    Ingram, Patrick
    Lou, Xia
    Yoon, Euisik
    Date
    2013-01
    Permanent link to this record
    http://hdl.handle.net/10754/599120
    
    Metadata
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    Abstract
    We present a novel design of micropumps and valves driven by osmotic force for point-of-care applications. Although there have been significant progresses in microfluidic components and control devices such as fluidic diodes, switches, resonators and digital-to-analog converters, the ultimate power source still depends on bulky off-chip components, which are expensive and cannot be easily miniaturized. For point-of-care applications, it is critical to integrate all the components in a compact size at low cost. In this work, we report two key active components actuated by osmotic mechanism for total integrated microfluidic system. For the proof of concept, we have demonstrated valve actuation, which can maintain stable ON/OFF switching operations under 125 kPa back pressure. We have also implemented an osmotic pump, which can pump a high flow rate over 30 μL/min for longer than 30 minutes. The experimental data demonstrates the possibility and potential of applying osmotic actuation in point-of-care disposable microfluidics. © 2013 IEEE.
    Citation
    Chen Y-C, Ingram P, Lou X, Yoon E (2013) Osmotic actuation for microfluidic components in point-of-care applications. 2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS). Available: http://dx.doi.org/10.1109/MEMSYS.2013.6474448.
    Sponsors
    This work was supported in part by the Thermo Fisher Scientific Screening Technology Grant under the Center for Chemical Genomics at the Life Sciences Institute at the University of Michigan, and in part by Academic Excellence Alliance Award from KAUST.
    Publisher
    Institute of Electrical and Electronics Engineers (IEEE)
    Journal
    2013 IEEE 26th International Conference on Micro Electro Mechanical Systems (MEMS)
    DOI
    10.1109/MEMSYS.2013.6474448
    ae974a485f413a2113503eed53cd6c53
    10.1109/MEMSYS.2013.6474448
    Scopus Count
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    Publications Acknowledging KAUST Support

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